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| 16.04.1981 | 20:00 | 1. FC Nürnberg | - | Bayern München | 0:1 (0:0) | |
| 20:00 | Hamburger SV | - | Arminia Bielefeld | 4:1 (2:0) | ||
| 20:00 | VfL Bochum | - | Fortuna Düsseldorf | 2:1 (1:1) | ||
| 20:00 | MSV Duisburg | - | Borussia Dortmund | 2:1 (0:1) | ||
| 18.04.1981 | 15:30 | 1. FC Köln | - | Bor. Mönchengladbach | 2:3 (0:1) | |
| 15:30 | Karlsruher SC | - | Eintracht Frankfurt | 1:1 (0:1) | ||
| 15:30 | VfB Stuttgart | - | SV Bayer 04 Leverkusen | 2:1 (1:1) | ||
| 15:30 | TSV 1860 München | - | FC Schalke 04 | 3:1 (2:0) | ||
| 15:30 | 1. FC Kaiserslautern | - | Bayer 05 Uerdingen | 4:2 (2:1) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Bayern München | 29 | 17 | 9 | 3 | 68:38 | 30 | 43:15 |
| 2 |
|
Hamburger SV | 29 | 19 | 5 | 5 | 67:37 | 30 | 43:15 |
| 3 |
|
1. FC Kaiserslautern | 29 | 14 | 9 | 6 | 54:33 | 21 | 37:21 |
| 4 |
|
VfB Stuttgart | 29 | 15 | 7 | 7 | 57:39 | 18 | 37:21 |
| 5 |
|
Eintracht Frankfurt | 29 | 13 | 9 | 7 | 53:40 | 13 | 35:23 |
| 6 |
|
VfL Bochum | 29 | 8 | 14 | 7 | 45:38 | 7 | 30:28 |
| 7 |
|
Bor. Mönchengladbach | 29 | 12 | 6 | 11 | 51:54 | -3 | 30:28 |
| 8 |
|
Borussia Dortmund | 29 | 11 | 7 | 11 | 61:53 | 8 | 29:29 |
| 9 |
|
1. FC Köln | 29 | 10 | 9 | 10 | 48:47 | 1 | 29:29 |
| 10 |
|
Karlsruher SC | 29 | 7 | 13 | 9 | 40:51 | -11 | 27:31 |
| 11 |
|
SV Bayer 04 Leverkusen | 29 | 8 | 9 | 12 | 44:47 | -3 | 25:33 |
| 12 |
|
Fortuna Düsseldorf | 29 | 9 | 7 | 13 | 52:56 | -4 | 25:33 |
| 13 |
|
MSV Duisburg | 29 | 8 | 9 | 12 | 36:49 | -13 | 25:33 |
| 14 |
|
TSV 1860 München | 29 | 8 | 6 | 15 | 43:55 | -12 | 22:36 |
| 15 |
|
1. FC Nürnberg | 29 | 9 | 4 | 16 | 41:53 | -12 | 22:36 |
| 16 |
|
FC Schalke 04 | 29 | 8 | 6 | 15 | 40:72 | -32 | 22:36 |
| 17 |
|
Bayer 05 Uerdingen | 29 | 8 | 5 | 16 | 44:62 | -18 | 21:37 |
| 18 |
|
Arminia Bielefeld | 29 | 7 | 6 | 16 | 39:59 | -20 | 20:38 |
