 |
 |
|
|
| H | Young Africans | - | Al Ahly SC | 1:1 (1:1) | ||
| R | Al Ahly SC | - | Young Africans | 2:1 (0:0) | ||
| H: 09.04.2016 15:00 | R: 20.04.2016 19:30 | Sieger: Al Ahly SC | ||||
| H | ASEC Mimosas | - | Al Ahly Tripolis | 2:0 (0:0) | ||
| R | Al Ahly Tripolis | - | ASEC Mimosas | 2:1 (1:1) | ||
| H: 09.04.2016 17:30 | R: 20.04.2016 17:00 | Sieger: ASEC Mimosas | ||||
| H | Al Merrikh SC | - | ES Sétif | 2:2 (1:2) | ||
| R | ES Sétif | - | Al Merrikh SC | 0:0 (0:0) | ||
| H: 09.04.2016 19:00 | R: 19.04.2016 20:00 | Sieger: ES Sétif | ||||
| H | Stade Malien | - | ZESCO United | 1:3 (1:1) | ||
| R | ZESCO United | - | Stade Malien | 2:1 (1:0) | ||
| H: 09.04.2016 20:00 | R: 19.04.2016 15:00 | Sieger: ZESCO United | ||||
| H | Zamalek | - | MO Béjaïa | 2:0 (0:0) | ||
| R | MO Béjaïa | - | Zamalek | 1:1 (0:0) | ||
| H: 09.04.2016 20:00 | R: 19.04.2016 19:00 | Sieger: Zamalek | ||||
| H | Wydad AC | - | TP Mazembe | 2:0 (1:0) | ||
| R | TP Mazembe | - | Wydad AC | 1:1 | ||
| H: 09.04.2016 20:30 | R: 20.04.2016 15:30 | Sieger: Wydad AC | ||||
| H | AS Vita Club | - | Mamelodi Sundowns | 1:0 (0:0) | ||
| R | Mamelodi Sundowns | - | AS Vita Club | 2:1 (1:1) | ||
| H: 10.04.2016 16:30 | R: 20.04.2016 19:30 | Sieger: AS Vita Club | ||||
| H | Enyimba Aba | - | Étoile du Sahel | 3:0 (1:0) | ||
| R | Étoile du Sahel | - | Enyimba Aba | 3:4 (1:0, 3:0) i.E. | ||
| H: 10.04.2016 17:00 | R: 20.04.2016 20:00 | Sieger: Enyimba Aba | ||||
