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| H | Shakhtar Donetsk | - | Sevilla FC | 2:2 (2:1) | ||
| R | Sevilla FC | - | Shakhtar Donetsk | 3:1 (1:1) | ||
| H: 28.04.2016 21:05 | R: 05.05.2016 21:05 | Sieger: Sevilla FC | ||||
| H | Villarreal CF | - | Liverpool FC | 1:0 (0:0) | ||
| R | Liverpool FC | - | Villarreal CF | 3:0 (1:0) | ||
| H: 28.04.2016 21:05 | R: 05.05.2016 21:05 | Sieger: Liverpool FC | ||||
