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| 18.02.2022 | 21:00 | Agropecuario Argentino | - | Estudiantes de Río Cuarto | 0:1 (0:0) | |
| 23:15 | Instituto de Córdoba | - | Alvarado | 0:0 (0:0) | ||
| 19.02.2022 | 01:30 | Defensores de Belgrano | - | Temperley | 0:2 (0:2) | |
| 21:00 | Atlanta | - | Güemes de SdE | 3:1 (0:0) | ||
| 21:00 | Tristan Suárez | - | Deportivo Madryn | 1:1 (0:0) | ||
| 21:00 | Chacarita Juniors | - | Gimnasia de Jujuy | 0:0 (0:0) | ||
| 21:00 | Sacachispas | - | Almagro | 0:1 (0:0) | ||
| 21:30 | San Martín de San Juan | - | All Boys | 0:1 (0:1) | ||
| 23:15 | San Martín de Tucumán | - | Deportivo Morón | 0:0 (0:0) | ||
| 20.02.2022 | 01:00 | Chaco For Ever | - | Gimnasia de Mendoza | 1:0 (1:0) | |
| 01:30 | Mitre de SdE | - | Nueva Chicago | 0:0 (0:0) | ||
| 21:00 | Brown de Adrogué | - | Flandria | 3:0 (2:0) | ||
| 21:00 | Estudiantes de Caseros | - | Deportivo Riestra | 0:0 (0:0) | ||
| 21:00 | Guillermo Brown | - | Almirante Brown | 3:1 (1:0) | ||
| 21:00 | Independiente Rivadavia | - | Quilmes | 1:0 (0:0) | ||
| 23:00 | Atlético Rafaela | - | Villa Dálmine | 1:1 (0:1) | ||
| 21.02.2022 | 21:00 | Ramón Santamarina | - | Belgrano de Córdoba | 0:1 (0:1) | |
| 23:15 | Ferro Carril Oeste | - | Deportivo Maipú | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Guillermo Brown | 2 | 2 | 0 | 0 | 5:2 | 3 | 6 |
| 2 |
|
Almagro | 2 | 2 | 0 | 0 | 3:1 | 2 | 6 |
| 3 |
|
All Boys | 2 | 2 | 0 | 0 | 2:0 | 2 | 6 |
|
Belgrano de Córdoba | 2 | 2 | 0 | 0 | 2:0 | 2 | 6 | |
| 5 |
|
Brown de Adrogué | 2 | 1 | 1 | 0 | 6:3 | 3 | 4 |
| 6 |
|
Deportivo Riestra | 2 | 1 | 1 | 0 | 2:0 | 2 | 4 |
| 7 |
|
Chaco For Ever | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 |
|
Deportivo Madryn | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 | |
|
Deportivo Maipú | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 | |
|
Estudiantes de Río Cuarto | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 | |
|
Independiente Rivadavia | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 | |
|
San Martín de Tucumán | 2 | 1 | 1 | 0 | 2:1 | 1 | 4 | |
| 13 |
|
Atlanta | 2 | 1 | 0 | 1 | 3:2 | 1 | 3 |
|
Temperley | 2 | 1 | 0 | 1 | 3:2 | 1 | 3 | |
| 15 |
|
Almirante Brown | 2 | 1 | 0 | 1 | 5:5 | 0 | 3 |
| 16 |
|
Ferro Carril Oeste | 2 | 1 | 0 | 1 | 1:1 | 0 | 3 |
|
San Martín de San Juan | 2 | 1 | 0 | 1 | 1:1 | 0 | 3 | |
| 18 |
|
Gimnasia de Jujuy | 2 | 0 | 2 | 0 | 3:3 | 0 | 2 |
| 19 |
|
Alvarado | 2 | 0 | 2 | 0 | 1:1 | 0 | 2 |
|
Estudiantes de Caseros | 2 | 0 | 2 | 0 | 1:1 | 0 | 2 | |
|
Instituto de Córdoba | 2 | 0 | 2 | 0 | 1:1 | 0 | 2 | |
|
Tristan Suárez | 2 | 0 | 2 | 0 | 1:1 | 0 | 2 | |
| 23 |
|
Deportivo Morón | 2 | 0 | 2 | 0 | 0:0 | 0 | 2 |
| 24 |
|
San Telmo | 1 | 0 | 1 | 0 | 1:1 | 0 | 1 |
| 25 |
|
Villa Dálmine | 2 | 0 | 1 | 1 | 2:3 | -1 | 1 |
| 26 |
|
Atlético Rafaela | 2 | 0 | 1 | 1 | 1:2 | -1 | 1 |
|
Mitre de SdE | 2 | 0 | 1 | 1 | 1:2 | -1 | 1 | |
|
Sacachispas | 2 | 0 | 1 | 1 | 1:2 | -1 | 1 | |
| 29 |
|
Nueva Chicago | 2 | 0 | 1 | 1 | 0:1 | -1 | 1 |
| 30 |
|
Chacarita Juniors | 2 | 0 | 1 | 1 | 2:4 | -2 | 1 |
|
Güemes de SdE | 2 | 0 | 1 | 1 | 2:4 | -2 | 1 | |
| 32 |
|
Defensores de Belgrano | 2 | 0 | 1 | 1 | 1:3 | -2 | 1 |
| 33 |
|
Flandria | 2 | 0 | 1 | 1 | 1:4 | -3 | 1 |
| 34 |
|
Quilmes | 1 | 0 | 0 | 1 | 0:1 | -1 | 0 |
| 35 |
|
Agropecuario Argentino | 2 | 0 | 0 | 2 | 0:2 | -2 | 0 |
|
Gimnasia de Mendoza | 2 | 0 | 0 | 2 | 0:2 | -2 | 0 | |
| 37 |
|
Ramón Santamarina | 2 | 0 | 0 | 2 | 0:3 | -3 | 0 |
| Aufstieg | |
| Playoffs | |
| Playoffs | |
| Abstieg |
