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| 11.03.2022 | 00:05 | Villa Dálmine | - | Atlanta | 0:0 (0:0) | |
| 22:05 | Almagro | - | Tristan Suárez | 1:0 (0:0) | ||
| 12.03.2022 | 00:10 | Belgrano de Córdoba | - | San Martín de San Juan | 2:0 (0:0) | |
| 01:30 | Estudiantes de Río Cuarto | - | Defensores de Belgrano | 0:2 (0:2) | ||
| 21:00 | Deportivo Riestra | - | Chaco For Ever | 1:1 (1:1) | ||
| 21:00 | Deportivo Madryn | - | Brown de Adrogué | 1:1 (0:0) | ||
| 21:00 | Flandria | - | Atlético Rafaela | 2:1 (0:1) | ||
| 21:00 | Quilmes | - | Sacachispas | 1:1 (0:0) | ||
| 23:05 | Temperley | - | Guillermo Brown | 0:1 (0:0) | ||
| 13.03.2022 | 01:10 | Almirante Brown | - | Estudiantes de Caseros | 1:0 (1:0) | |
| 01:30 | Güemes de SdE | - | San Telmo | 0:1 (0:0) | ||
| 21:00 | All Boys | - | Gimnasia de Mendoza | 1:1 (1:1) | ||
| 21:00 | Alvarado | - | San Martín de Tucumán | 3:1 (0:1) | ||
| 21:00 | Deportivo Maipú | - | Instituto de Córdoba | 1:1 (0:0) | ||
| 21:00 | Gimnasia de Jujuy | - | Ramón Santamarina | 1:0 (0:0) | ||
| 21:05 | Deportivo Morón | - | Chacarita Juniors | 0:1 (0:1) | ||
| 14.03.2022 | 00:00 | Independiente Rivadavia | - | Mitre de SdE | 1:0 (0:0) | |
| 23:00 | Nueva Chicago | - | Agropecuario Argentino | 1:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Belgrano de Córdoba | 5 | 4 | 1 | 0 | 7:2 | 5 | 13 |
| 2 |
|
Guillermo Brown | 5 | 4 | 0 | 1 | 8:5 | 3 | 12 |
| 3 |
|
Brown de Adrogué | 5 | 3 | 2 | 0 | 9:4 | 5 | 11 |
| 4 |
|
Deportivo Riestra | 5 | 3 | 2 | 0 | 5:1 | 4 | 11 |
| 5 |
|
Almirante Brown | 5 | 3 | 1 | 1 | 9:7 | 2 | 10 |
| 6 |
|
San Martín de Tucumán | 5 | 3 | 1 | 1 | 7:5 | 2 | 10 |
| 7 |
|
Almagro | 5 | 3 | 1 | 1 | 6:4 | 2 | 10 |
| 8 |
|
All Boys | 5 | 2 | 3 | 0 | 6:4 | 2 | 9 |
| 9 |
|
Deportivo Maipú | 5 | 2 | 3 | 0 | 5:3 | 2 | 9 |
|
Instituto de Córdoba | 5 | 2 | 3 | 0 | 5:3 | 2 | 9 | |
| 11 |
|
Independiente Rivadavia | 4 | 2 | 2 | 0 | 3:1 | 2 | 8 |
| 12 |
|
Deportivo Madryn | 5 | 2 | 2 | 1 | 6:5 | 1 | 8 |
| 13 |
|
Chacarita Juniors | 5 | 2 | 2 | 1 | 7:7 | 0 | 8 |
|
Gimnasia de Jujuy | 5 | 2 | 2 | 1 | 7:7 | 0 | 8 | |
| 15 |
|
Alvarado | 5 | 1 | 4 | 0 | 7:5 | 2 | 7 |
| 16 |
|
Quilmes | 4 | 2 | 1 | 1 | 6:4 | 2 | 7 |
| 17 |
|
Chaco For Ever | 5 | 1 | 4 | 0 | 5:4 | 1 | 7 |
| 18 |
|
Atlanta | 5 | 1 | 2 | 2 | 4:4 | 0 | 5 |
| 19 |
|
Defensores de Belgrano | 5 | 1 | 2 | 2 | 5:6 | -1 | 5 |
| 20 |
|
Nueva Chicago | 5 | 1 | 2 | 2 | 3:4 | -1 | 5 |
| 21 |
|
San Telmo | 4 | 1 | 2 | 1 | 3:5 | -2 | 5 |
| 22 |
|
Estudiantes de Río Cuarto | 5 | 1 | 2 | 2 | 3:6 | -3 | 5 |
| 23 |
|
Gimnasia de Mendoza | 4 | 1 | 1 | 2 | 4:3 | 1 | 4 |
| 24 |
|
Atlético Rafaela | 5 | 1 | 1 | 3 | 5:5 | 0 | 4 |
| 25 |
|
Ramón Santamarina | 5 | 1 | 1 | 3 | 5:6 | -1 | 4 |
|
Temperley | 5 | 1 | 1 | 3 | 5:6 | -1 | 4 | |
|
Tristan Suárez | 5 | 0 | 4 | 1 | 5:6 | -1 | 4 | |
| 28 |
|
Sacachispas | 5 | 0 | 4 | 1 | 4:5 | -1 | 4 |
| 29 |
|
Ferro Carril Oeste | 4 | 1 | 1 | 2 | 2:3 | -1 | 4 |
| 30 |
|
San Martín de San Juan | 5 | 1 | 1 | 3 | 2:5 | -3 | 4 |
| 31 |
|
Flandria | 5 | 1 | 1 | 3 | 4:8 | -4 | 4 |
| 32 |
|
Estudiantes de Caseros | 5 | 0 | 3 | 2 | 4:6 | -2 | 3 |
| 33 |
|
Deportivo Morón | 5 | 0 | 3 | 2 | 1:3 | -2 | 3 |
| 34 |
|
Güemes de SdE | 5 | 0 | 3 | 2 | 3:6 | -3 | 3 |
| 35 |
|
Villa Dálmine | 5 | 0 | 3 | 2 | 4:8 | -4 | 3 |
| 36 |
|
Agropecuario Argentino | 5 | 0 | 2 | 3 | 2:5 | -3 | 2 |
| 37 |
|
Mitre de SdE | 5 | 0 | 1 | 4 | 2:7 | -5 | 1 |
| Aufstieg | |
| Playoffs | |
| Playoffs | |
| Abstieg |
