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| 21.04.2018 | 00:00 | Argentinos Juniors | - | Olimpo de Bahía Blanca | 1:0 (1:0) | |
| 02:15 | Estudiantes | - | Belgrano de Córdoba | 0:1 (0:0) | ||
| 18:15 | San Martín de San Juan | - | Lanús | 1:1 (1:1) | ||
| 18:15 | Temperley | - | Vélez Sarsfield | 2:4 (1:2) | ||
| 20:30 | Talleres de Córdoba | - | Gimnasia de La Plata | 2:0 (0:0) | ||
| 22:45 | Banfield | - | Godoy Cruz | 1:1 (0:0) | ||
| 22.04.2018 | 01:00 | San Lorenzo | - | Chacarita Juniors | 1:0 (1:0) | |
| 16:00 | Tigre | - | Huracán | 0:2 (0:2) | ||
| 18:15 | Rosario Central | - | Racing Club | 0:2 (0:0) | ||
| 20:30 | Atlético Tucumán | - | Unión de Santa Fe | 0:0 (0:0) | ||
| 22:45 | Arsenal de Sarandí | - | River Plate | 0:3 (0:3) | ||
| 23.04.2018 | 01:00 | Boca Juniors | - | Newell's Old Boys | 3:1 (2:1) | |
| 24.04.2018 | 00:00 | Colón de Santa Fe | - | Patronato de Paraná | 4:0 (2:0) | |
| 02:15 | Independiente | - | Defensa y Justicia | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Boca Juniors | 24 | 17 | 2 | 5 | 43:17 | 26 | 53 |
| 2 |
|
Godoy Cruz | 24 | 14 | 5 | 5 | 39:23 | 16 | 47 |
| 3 |
|
San Lorenzo | 24 | 13 | 7 | 4 | 29:18 | 11 | 46 |
| 4 |
|
Talleres de Córdoba | 24 | 13 | 5 | 6 | 31:15 | 16 | 44 |
| 5 |
|
Huracán | 24 | 12 | 7 | 5 | 29:19 | 10 | 43 |
| 6 |
|
Independiente | 24 | 12 | 6 | 6 | 26:16 | 10 | 42 |
| 7 |
|
Racing Club | 24 | 11 | 6 | 7 | 41:28 | 13 | 39 |
| 8 |
|
Argentinos Juniors | 24 | 12 | 3 | 9 | 34:27 | 7 | 39 |
| 9 |
|
River Plate | 24 | 11 | 5 | 8 | 35:26 | 9 | 38 |
| 10 |
|
Defensa y Justicia | 24 | 11 | 5 | 8 | 36:32 | 4 | 38 |
| 11 |
|
Colón de Santa Fe | 24 | 10 | 7 | 7 | 29:20 | 9 | 37 |
| 12 |
|
Unión de Santa Fe | 24 | 9 | 10 | 5 | 29:21 | 8 | 37 |
| 13 |
|
Belgrano de Córdoba | 24 | 9 | 10 | 5 | 26:23 | 3 | 37 |
| 14 |
|
Estudiantes | 24 | 10 | 5 | 9 | 23:21 | 2 | 35 |
| 15 |
|
Atlético Tucumán | 24 | 8 | 10 | 6 | 26:22 | 4 | 34 |
| 16 |
|
Banfield | 24 | 8 | 7 | 9 | 25:22 | 3 | 31 |
| 17 |
|
Vélez Sarsfield | 24 | 8 | 7 | 9 | 27:31 | -4 | 31 |
| 18 |
|
Rosario Central | 24 | 8 | 7 | 9 | 28:33 | -5 | 31 |
| 19 |
|
San Martín de San Juan | 24 | 8 | 6 | 10 | 26:31 | -5 | 30 |
| 20 |
|
Patronato de Paraná | 24 | 7 | 7 | 10 | 24:31 | -7 | 28 |
| 21 |
|
Lanús | 24 | 6 | 8 | 10 | 20:37 | -17 | 26 |
| 22 |
|
Newell's Old Boys | 24 | 7 | 6 | 11 | 22:25 | -3 | 24 |
| 23 |
|
Gimnasia de La Plata | 24 | 6 | 4 | 14 | 22:39 | -17 | 22 |
| 24 |
|
Tigre | 24 | 3 | 11 | 10 | 21:30 | -9 | 20 |
| 25 |
|
Chacarita Juniors | 24 | 4 | 6 | 14 | 20:32 | -12 | 18 |
| 26 |
|
Temperley | 24 | 3 | 8 | 13 | 16:41 | -25 | 17 |
| 27 |
|
Arsenal de Sarandí | 24 | 2 | 8 | 14 | 15:32 | -17 | 14 |
| 28 |
|
Olimpo de Bahía Blanca | 24 | 3 | 4 | 17 | 12:42 | -30 | 13 |
| Copa Libertadores | |
| Copa Sudamericana |
|
# Newell's Old Boys wurden wegen ausstehender Zahlungen an ehemalige Spieler drei Punkte abgezogen. |
