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| 02.04.1999 | 20:00 | RSC Anderlecht | - | Sporting Lokeren | 1:1 (0:1) | |
| 03.04.1999 | 20:00 | KRC Harelbeke | - | K.S.C. Eendracht Aalst | 5:1 (3:0) | |
| 20:00 | Club Brugge KV | - | KAA Gent | 1:0 (0:0) | ||
| 20:00 | Lommelse SK | - | Lierse SK | 0:0 (0:0) | ||
| 20:00 | KSK Beveren | - | RSC Charleroi | 1:2 (0:0) | ||
| 20:00 | Excelsior Mouscron | - | KV Kortrijk | 3:1 (0:0) | ||
| 20:00 | KVC Westerlo | - | KRC Genk | 1:1 (0:0) | ||
| 20:00 | Germinal Beerschot | - | Standard Liège | 0:1 (0:0) | ||
| 20:00 | Sint-Truidense VV | - | KV Oostende | 5:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KRC Genk | 28 | 18 | 6 | 4 | 60:30 | 30 | 60 |
| 2 |
|
Club Brugge KV | 28 | 18 | 4 | 6 | 51:30 | 21 | 58 |
| 3 |
|
RSC Anderlecht | 28 | 16 | 6 | 6 | 55:36 | 19 | 54 |
| 4 |
|
Excelsior Mouscron | 28 | 15 | 7 | 6 | 64:43 | 21 | 52 |
| 5 |
|
Standard Liège | 28 | 16 | 2 | 10 | 50:30 | 20 | 50 |
| 6 |
|
KAA Gent | 28 | 13 | 8 | 7 | 48:48 | 0 | 47 |
| 7 |
|
Sint-Truidense VV | 28 | 13 | 7 | 8 | 46:35 | 11 | 46 |
| 8 |
|
Sporting Lokeren | 28 | 13 | 6 | 9 | 53:49 | 4 | 45 |
| 9 |
|
Lierse SK | 28 | 13 | 5 | 10 | 57:40 | 17 | 44 |
| 10 |
|
Germinal Beerschot | 28 | 11 | 6 | 11 | 39:39 | 0 | 39 |
| 11 |
|
KRC Harelbeke | 28 | 9 | 9 | 10 | 39:40 | -1 | 36 |
| 12 |
|
KVC Westerlo | 28 | 10 | 5 | 13 | 48:50 | -2 | 35 |
| 13 |
|
K.S.C. Eendracht Aalst | 28 | 8 | 7 | 13 | 39:51 | -12 | 31 |
| 14 |
|
RSC Charleroi | 28 | 6 | 11 | 11 | 35:43 | -8 | 29 |
| 15 |
|
Lommelse SK | 28 | 5 | 5 | 18 | 24:45 | -21 | 20 |
| 16 |
|
KSK Beveren | 28 | 5 | 5 | 18 | 27:54 | -27 | 20 |
| 17 |
|
KV Kortrijk | 28 | 4 | 6 | 18 | 37:68 | -31 | 18 |
| 18 |
|
KV Oostende | 28 | 2 | 9 | 17 | 23:64 | -41 | 15 |
