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| 08.05.1999 | 20:00 | KVC Westerlo | - | K.S.C. Eendracht Aalst | 1:1 (1:0) | |
| 09.05.1999 | 15:00 | Standard Liège | - | Sporting Lokeren | 2:4 (0:3) | |
| 15:00 | KV Kortrijk | - | Lommelse SK | 4:1 (1:1) | ||
| 15:00 | Excelsior Mouscron | - | Club Brugge KV | 2:0 (1:0) | ||
| 15:00 | KV Oostende | - | Lierse SK | 0:6 (0:1) | ||
| 15:00 | KSK Beveren | - | Germinal Beerschot | 2:1 (1:0) | ||
| 15:00 | KAA Gent | - | KRC Harelbeke | 0:0 (0:0) | ||
| 15:00 | RSC Charleroi | - | Sint-Truidense VV | 2:1 (1:1) | ||
| 20:00 | KRC Genk | - | RSC Anderlecht | 2:5 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
KRC Genk | 33 | 21 | 7 | 5 | 72:37 | 35 | 70 |
| 2 |
|
Club Brugge KV | 33 | 21 | 5 | 7 | 60:35 | 25 | 68 |
| 3 |
|
RSC Anderlecht | 33 | 20 | 7 | 6 | 73:38 | 35 | 67 |
| 4 |
|
Excelsior Mouscron | 33 | 19 | 8 | 6 | 75:46 | 29 | 65 |
| 5 |
|
Sporting Lokeren | 33 | 17 | 6 | 10 | 68:57 | 11 | 57 |
| 6 |
|
Standard Liège | 33 | 17 | 3 | 13 | 55:44 | 11 | 54 |
| 7 |
|
Lierse SK | 33 | 15 | 6 | 12 | 69:47 | 22 | 51 |
| 8 |
|
Sint-Truidense VV | 33 | 14 | 8 | 11 | 51:45 | 6 | 50 |
| 9 |
|
KAA Gent | 33 | 13 | 10 | 10 | 51:58 | -7 | 49 |
| 10 |
|
Germinal Beerschot | 33 | 14 | 6 | 13 | 47:45 | 2 | 48 |
| 11 |
|
KRC Harelbeke | 33 | 10 | 11 | 12 | 43:44 | -1 | 41 |
| 12 |
|
KVC Westerlo | 33 | 11 | 7 | 15 | 53:57 | -4 | 40 |
| 13 |
|
RSC Charleroi | 33 | 7 | 11 | 15 | 39:52 | -13 | 32 |
| 14 |
|
K.S.C. Eendracht Aalst | 33 | 8 | 8 | 17 | 44:66 | -22 | 32 |
| 15 |
|
KSK Beveren | 33 | 8 | 5 | 20 | 32:59 | -27 | 29 |
| 16 |
|
Lommelse SK | 33 | 6 | 7 | 20 | 31:55 | -24 | 25 |
| 17 |
|
KV Kortrijk | 33 | 6 | 7 | 20 | 48:78 | -30 | 25 |
| 18 |
|
KV Oostende | 33 | 4 | 10 | 19 | 27:75 | -48 | 22 |
