 |
 |
|
|
| 14.12.2021 | 18:45 | Cercle Brugge | - | RFC Seraing | 2:0 (2:0) | |
| 21:00 | KV Oostende | - | KV Kortrijk | 0:2 (0:1) | ||
| 21:00 | RSC Anderlecht | - | Sint-Truidense VV | 2:0 (0:0) | ||
| 15.12.2021 | 18:45 | KV Mechelen | - | KAA Gent | 4:3 (1:1) | |
| 18:45 | SV Zulte Waregem | - | Union Saint-Gilloise | 0:2 (0:2) | ||
| 21:00 | Oud-Heverlee Leuven | - | Club Brugge KV | 1:4 (0:1) | ||
| 16.12.2021 | 18:45 | Royal Antwerp FC | - | KAS Eupen | 4:2 (2:1) | |
| 21:00 | KRC Genk | - | Sporting Charleroi | 4:2 (2:2) | ||
| 02.03.2022 | 18:45 | Standard Liège | - | K Beerschot VA | 1:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Union Saint-Gilloise | 19 | 14 | 1 | 4 | 47:18 | 29 | 43 |
| 2 |
|
Club Brugge KV | 19 | 11 | 6 | 2 | 39:24 | 15 | 39 |
| 3 |
|
Royal Antwerp FC | 19 | 11 | 3 | 5 | 36:23 | 13 | 36 |
| 4 |
|
RSC Anderlecht | 19 | 9 | 7 | 3 | 41:24 | 17 | 34 |
| 5 |
|
Sporting Charleroi | 19 | 9 | 5 | 5 | 34:26 | 8 | 32 |
| 6 |
|
KAA Gent | 19 | 9 | 3 | 7 | 31:21 | 10 | 30 |
| 7 |
|
KV Mechelen | 19 | 9 | 3 | 7 | 33:34 | -1 | 30 |
| 8 |
|
KV Kortrijk | 19 | 7 | 7 | 5 | 24:22 | 2 | 28 |
| 9 |
|
Standard Liège | 19 | 7 | 5 | 7 | 22:31 | -9 | 26 |
| 10 |
|
KRC Genk | 19 | 7 | 4 | 8 | 35:32 | 3 | 25 |
| 11 |
|
KAS Eupen | 19 | 7 | 4 | 8 | 30:30 | 0 | 25 |
| 12 |
|
Cercle Brugge | 19 | 6 | 4 | 9 | 24:25 | -1 | 22 |
| 13 |
|
Sint-Truidense VV | 19 | 6 | 3 | 10 | 19:29 | -10 | 21 |
| 14 |
|
Oud-Heverlee Leuven | 19 | 4 | 8 | 7 | 24:33 | -9 | 20 |
| 15 |
|
KV Oostende | 19 | 6 | 2 | 11 | 21:39 | -18 | 20 |
| 16 |
|
RFC Seraing | 19 | 6 | 1 | 12 | 23:38 | -15 | 19 |
| 17 |
|
SV Zulte Waregem | 19 | 4 | 5 | 10 | 27:43 | -16 | 17 |
| 18 |
|
K Beerschot VA | 19 | 2 | 3 | 14 | 15:33 | -18 | 9 |
| Playoffs | |
| Playoffs | |
| Relegation | |
| Abstieg |
