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| H | Neman Grodno | - | BATE Borisov | 2:1 (0:1) | ||
| R | BATE Borisov | - | Neman Grodno | 2:0 (1:0) | ||
| H: 06.04.2022 16:00 | R: 27.04.2022 18:30 | Sieger: BATE Borisov | ||||
| H | FK Gomel | - | FK Vitebsk | 2:0 (1:0) | ||
| R | FK Vitebsk | - | FK Gomel | 1:0 (0:0) | ||
| H: 07.04.2022 16:00 | R: 27.04.2022 16:00 | Sieger: FK Gomel | ||||
