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| H | Once Caldas | - | Deportes Tolima | 1:0 (1:0) | ||
| R | Deportes Tolima | - | Once Caldas | 3:1 (1:1) | ||
| H: 28.11.2015 23:30 | R: 05.12.2015 23:30 | Sieger: Deportes Tolima | ||||
| H | Santa Fe | - | Atlético Junior | 2:1 (1:1) | ||
| R | Atlético Junior | - | Santa Fe | 3:1 (2:1) | ||
| H: 29.11.2015 01:45 | R: 06.12.2015 23:00 | Sieger: Atlético Junior | ||||
| H | Deportivo Cali | - | Atlético Nacional | 0:0 (0:0) | ||
| R | Atlético Nacional | - | Deportivo Cali | 3:1 (2:1) | ||
| H: 29.11.2015 23:00 | R: 06.12.2015 02:00 | Sieger: Atlético Nacional | ||||
| H | Alianza Petrolera | - | Independiente Medellín | 0:2 (0:2) | ||
| R | Independiente Medellín | - | Alianza Petrolera | 4:0 (1:0) | ||
| H: 30.11.2015 01:30 | R: 07.12.2015 01:30 | Sieger: Independiente Medellín | ||||
