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| H | La Equidad | - | Santa Fe | 1:1 (0:1) | ||
| R | Santa Fe | - | La Equidad | 2:1 (1:0) | ||
| H: 06.12.2020 02:00 | R: 13.12.2020 01:30 | Sieger: Santa Fe | ||||
| H | América de Cali | - | Atlético Junior | 0:0 (0:0) | ||
| R | Atlético Junior | - | América de Cali | 1:2 (0:2) | ||
| H: 07.12.2020 02:00 | R: 14.12.2020 02:00 | Sieger: América de Cali | ||||
