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| 30.04.2022 | 03:00 | Deportivo Pereira | - | Unión Magdalena | 2:0 (2:0) | |
| 21:00 | La Equidad | - | Atlético Bucaramanga | 1:1 (1:1) | ||
| 23:05 | Independiente Medellín | - | Atlético Nacional | 0:0 (0:0) | ||
| 01.05.2022 | 01:10 | Santa Fe | - | Jaguares de Córdoba | 4:0 (1:0) | |
| 03:15 | Deportes Tolima | - | Cortuluá | 3:2 (1:0) | ||
| 21:00 | Once Caldas | - | Deportivo Cali | 0:1 (0:1) | ||
| 23:05 | Patriotas FC | - | Millonarios | 1:2 (0:1) | ||
| 02.05.2022 | 03:15 | Atlético Junior | - | Envigado FC | 4:0 (2:0) | |
| 03.05.2022 | 00:00 | Águilas Doradas | - | Deportivo Pasto | 1:0 (0:0) | |
| 02:30 | América de Cali | - | Alianza Petrolera | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Deportes Tolima | 18 | 12 | 2 | 4 | 28:13 | 15 | 38 |
| 2 |
|
Millonarios | 18 | 12 | 2 | 4 | 22:11 | 11 | 38 |
| 3 |
|
Atlético Nacional | 18 | 10 | 5 | 3 | 25:13 | 12 | 35 |
| 4 |
|
Atlético Junior | 18 | 10 | 2 | 6 | 28:16 | 12 | 32 |
| 5 |
|
Independiente Medellín | 18 | 9 | 4 | 5 | 24:16 | 8 | 31 |
| 6 |
|
Envigado FC | 18 | 7 | 6 | 5 | 20:20 | 0 | 27 |
| 7 |
|
La Equidad | 18 | 6 | 8 | 4 | 19:15 | 4 | 26 |
| 8 |
|
Alianza Petrolera | 18 | 6 | 8 | 4 | 20:19 | 1 | 26 |
| 9 |
|
Santa Fe | 18 | 7 | 4 | 7 | 26:23 | 3 | 25 |
| 10 |
|
Once Caldas | 18 | 6 | 7 | 5 | 16:14 | 2 | 25 |
| 11 |
|
Atlético Bucaramanga | 18 | 7 | 4 | 7 | 23:24 | -1 | 25 |
| 12 |
|
Águilas Doradas | 18 | 7 | 3 | 8 | 15:23 | -8 | 24 |
| 13 |
|
Deportivo Pereira | 18 | 6 | 4 | 8 | 20:22 | -2 | 22 |
| 14 |
|
Jaguares de Córdoba | 18 | 6 | 3 | 9 | 19:27 | -8 | 21 |
| 15 |
|
América de Cali | 18 | 5 | 5 | 8 | 18:22 | -4 | 20 |
| 16 |
|
Deportivo Pasto | 18 | 4 | 7 | 7 | 13:18 | -5 | 19 |
| 17 |
|
Patriotas FC | 18 | 4 | 5 | 9 | 15:22 | -7 | 17 |
| 18 |
|
Deportivo Cali | 18 | 4 | 5 | 9 | 13:20 | -7 | 17 |
| 19 |
|
Cortuluá | 18 | 4 | 4 | 10 | 18:25 | -7 | 16 |
| 20 |
|
Unión Magdalena | 18 | 2 | 4 | 12 | 7:26 | -19 | 10 |
| Nächste Runde |
