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| H | Universidad Católica | - | São Paulo FC | 1:1 (0:1) | ||
| R | São Paulo FC | - | Universidad Católica | 0:0 (0:0) | ||
| H: 22.11.2012 23:15 | R: 29.11.2012 00:50 | Sieger: São Paulo FC | ||||
| H | Tigre | - | Millonarios | 0:0 (0:0) | ||
| R | Millonarios | - | Tigre | 1:1 (0:0) | ||
| H: 23.11.2012 01:45 | R: 30.11.2012 01:15 | Sieger: Tigre | ||||
