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| 12.02.2021 | 18:00 | 1. FC Slovácko | - | FK Teplice | 2:0 (1:0) | |
| 13.02.2021 | 14:00 | Zbrojovka Brno | - | FC Fastav Zlín | 0:0 (0:0) | |
| 14:00 | SFC Opava | - | 1. FK Příbram | 0:0 (0:0) | ||
| 16:00 | Slavia Praha | - | FK Pardubice | 3:0 (2:0) | ||
| 14.02.2021 | 14:00 | Baník Ostrava | - | FK Jablonec | 2:1 (2:1) | |
| 14:00 | Bohemians Praha 1905 | - | Sigma Olomouc | 0:0 (0:0) | ||
| 14:00 | FK Mladá Boleslav | - | Viktoria Plzeň | 2:2 (1:1) | ||
| 14:00 | Slovan Liberec | - | Dynamo České Budějovice | 0:0 (0:0) | ||
| 16:00 | AC Sparta Praha | - | MFK Karviná | 4:3 (3:2) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slavia Praha | 19 | 16 | 3 | 0 | 57:11 | 46 | 51 |
| 2 |
|
AC Sparta Praha | 19 | 13 | 2 | 4 | 40:24 | 16 | 41 |
| 3 |
|
1. FC Slovácko | 19 | 11 | 4 | 4 | 35:17 | 18 | 37 |
| 4 |
|
FK Jablonec | 19 | 11 | 2 | 6 | 34:24 | 10 | 35 |
| 5 |
|
Slovan Liberec | 19 | 9 | 5 | 5 | 27:17 | 10 | 32 |
| 6 |
|
Baník Ostrava | 19 | 8 | 5 | 6 | 23:17 | 6 | 29 |
| 7 |
|
Dynamo České Budějovice | 19 | 7 | 8 | 4 | 24:23 | 1 | 29 |
| 8 |
|
Viktoria Plzeň | 19 | 8 | 4 | 7 | 34:25 | 9 | 28 |
| 9 |
|
FK Pardubice | 19 | 8 | 4 | 7 | 17:22 | -5 | 28 |
| 10 |
|
Sigma Olomouc | 19 | 6 | 9 | 4 | 28:23 | 5 | 27 |
| 11 |
|
MFK Karviná | 19 | 6 | 6 | 7 | 23:30 | -7 | 24 |
| 12 |
|
Bohemians Praha 1905 | 19 | 6 | 5 | 8 | 21:23 | -2 | 23 |
| 13 |
|
FC Fastav Zlín | 19 | 6 | 4 | 9 | 20:26 | -6 | 22 |
| 14 |
|
FK Teplice | 19 | 5 | 2 | 12 | 18:40 | -22 | 17 |
| 15 |
|
Zbrojovka Brno | 19 | 3 | 5 | 11 | 16:33 | -17 | 14 |
| 16 |
|
FK Mladá Boleslav | 19 | 2 | 6 | 11 | 21:35 | -14 | 12 |
| 17 |
|
1. FK Příbram | 19 | 2 | 6 | 11 | 15:36 | -21 | 12 |
| 18 |
|
SFC Opava | 19 | 1 | 6 | 12 | 12:39 | -27 | 9 |
| Champions League Quali. | |
| Europa League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
