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| 16.04.2021 | 18:00 | Bohemians Praha 1905 | - | Baník Ostrava | 1:1 (0:0) | |
| 17.04.2021 | 14:00 | FK Mladá Boleslav | - | SFC Opava | 2:0 (0:0) | |
| 16:00 | MFK Karviná | - | Dynamo České Budějovice | 3:0 (2:0) | ||
| 16:00 | Sigma Olomouc | - | FK Teplice | 1:1 (1:0) | ||
| 18:30 | Viktoria Plzeň | - | FK Jablonec | 1:1 (1:0) | ||
| 18.04.2021 | 14:00 | Zbrojovka Brno | - | FK Pardubice | 1:2 (0:1) | |
| 14:00 | FC Fastav Zlín | - | 1. FK Příbram | 0:1 (0:0) | ||
| 16:00 | Slovan Liberec | - | Slavia Praha | 0:1 (0:0) | ||
| 18:30 | AC Sparta Praha | - | 1. FC Slovácko | 1:0 (0:0) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slavia Praha | 27 | 22 | 5 | 0 | 73:15 | 58 | 71 |
| 2 |
|
AC Sparta Praha | 27 | 18 | 3 | 6 | 58:30 | 28 | 57 |
| 3 |
|
FK Jablonec | 27 | 16 | 5 | 6 | 45:29 | 16 | 53 |
| 4 |
|
1. FC Slovácko | 27 | 15 | 5 | 7 | 47:27 | 20 | 50 |
| 5 |
|
Viktoria Plzeň | 27 | 13 | 6 | 8 | 46:32 | 14 | 45 |
| 6 |
|
Slovan Liberec | 27 | 12 | 7 | 8 | 37:24 | 13 | 43 |
| 7 |
|
FK Pardubice | 27 | 12 | 5 | 10 | 29:35 | -6 | 41 |
| 8 |
|
Baník Ostrava | 27 | 10 | 8 | 9 | 37:26 | 11 | 38 |
| 9 |
|
Sigma Olomouc | 27 | 9 | 11 | 7 | 33:27 | 6 | 38 |
| 10 |
|
Bohemians Praha 1905 | 27 | 8 | 10 | 9 | 29:29 | 0 | 34 |
| 11 |
|
MFK Karviná | 27 | 8 | 9 | 10 | 31:39 | -8 | 33 |
| 12 |
|
Dynamo České Budějovice | 27 | 7 | 10 | 10 | 27:38 | -11 | 31 |
| 13 |
|
FC Fastav Zlín | 27 | 8 | 5 | 14 | 26:37 | -11 | 29 |
| 14 |
|
FK Mladá Boleslav | 27 | 6 | 9 | 12 | 34:43 | -9 | 27 |
| 15 |
|
FK Teplice | 27 | 6 | 6 | 15 | 29:57 | -28 | 24 |
| 16 |
|
Zbrojovka Brno | 27 | 4 | 8 | 15 | 22:41 | -19 | 20 |
| 17 |
|
1. FK Příbram | 27 | 3 | 8 | 16 | 18:54 | -36 | 17 |
| 18 |
|
SFC Opava | 27 | 3 | 6 | 18 | 16:54 | -38 | 15 |
| Champions League Quali. | |
| Europa League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
