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| 05.11.2010 | 20:15 | Slavia Praha | - | FK Baumit Jablonec | 0:3 (0:2) | |
| 06.11.2010 | 16:00 | Slovan Liberec | - | FC Hradec Králové | 3:0 (0:0) | |
| 18:20 | Baník Ostrava | - | Viktoria Plzeň | 0:2 (0:1) | ||
| 07.11.2010 | 17:00 | Zbrojovka Brno | - | 1. FK Příbram | 0:1 (0:0) | |
| 17:00 | FK Mladá Boleslav | - | 1. FC Slovácko | 2:3 (0:1) | ||
| 17:00 | Sigma Olomouc | - | Dynamo České Budějovice | 5:1 (2:0) | ||
| 17:00 | FK Teplice | - | Bohemians 1905 | 0:2 (0:1) | ||
| 08.11.2010 | 18:00 | AC Sparta Praha | - | FK Ústí nad Labem | 4:1 (1:0) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Viktoria Plzeň | 15 | 13 | 1 | 1 | 42:14 | 28 | 40 |
| 2 |
|
AC Sparta Praha | 15 | 10 | 1 | 4 | 25:11 | 14 | 31 |
| 3 |
|
Sigma Olomouc | 15 | 8 | 4 | 3 | 29:10 | 19 | 28 |
| 4 |
|
FK Baumit Jablonec | 15 | 7 | 3 | 5 | 26:16 | 10 | 24 |
| 5 |
|
FK Mladá Boleslav | 15 | 6 | 6 | 3 | 25:19 | 6 | 24 |
| 6 |
|
FK Teplice | 15 | 7 | 3 | 5 | 20:20 | 0 | 24 |
| 7 |
|
Slovan Liberec | 15 | 5 | 4 | 6 | 20:20 | 0 | 19 |
| 8 |
|
1. FC Slovácko | 15 | 6 | 1 | 8 | 17:25 | -8 | 19 |
| 9 |
|
Dynamo České Budějovice | 15 | 4 | 6 | 5 | 12:23 | -11 | 18 |
| 10 |
|
FC Hradec Králové | 15 | 4 | 5 | 6 | 12:18 | -6 | 17 |
| 11 |
|
1. FK Příbram | 15 | 4 | 5 | 6 | 9:15 | -6 | 17 |
| 12 |
|
Bohemians 1905 | 15 | 4 | 4 | 7 | 17:20 | -3 | 16 |
| 13 |
|
Slavia Praha | 15 | 3 | 6 | 6 | 16:21 | -5 | 15 |
| 14 |
|
Baník Ostrava | 15 | 4 | 3 | 8 | 16:22 | -6 | 15 |
| 15 |
|
Zbrojovka Brno | 15 | 4 | 0 | 11 | 19:31 | -12 | 12 |
| 16 |
|
FK Ústí nad Labem | 15 | 2 | 6 | 7 | 11:31 | -20 | 12 |
| Champions League Quali. | |
| Europa League | |
| Abstieg |
