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| H | LDU Quito | - | Independiente del Valle | 1:0 | ||
| R | Independiente del Valle | - | LDU Quito | 5:6 i.E. | ||
| H: 09.11.2024 16:30 | R: 16.11.2024 15:00 | Sieger: LDU Quito | ||||
| H | Independiente Juniors | - | Universidad Catolica | 2:0 | ||
| R | Universidad Catolica | - | Independiente Juniors | 0:1 | ||
| H: 09.11.2024 17:00 | R: 16.11.2024 19:00 | Sieger: Independiente Juniors | ||||
| H | Delfin SC | - | Barcelona | 1:0 | ||
| R | Barcelona | - | Delfin SC | 2:1 | ||
| H: 09.11.2024 17:00 | R: 16.11.2024 20:15 | Sieger: Delfin SC | ||||
| H | Orense SC | - | Manta FC | 2:0 | ||
| R | Manta FC | - | Orense SC | 4:3 | ||
| H: 09.11.2024 19:15 | R: 16.11.2024 17:00 | Sieger: Orense SC | ||||
