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| H | Deportivo La Coruña | - | UD Las Palmas | 2:1 (1:1) | ||
| R | UD Las Palmas | - | Deportivo La Coruña | 1:3 (1:0, 2:1) i.E. | ||
| H: 13.06.2021 12:00 | R: 20.06.2021 12:00 | Sieger: Deportivo La Coruña | ||||
| H | Málaga CF | - | Athletic Bilbao | 2:0 (0:0) | ||
| R | Athletic Bilbao | - | Málaga CF | 3:3 (1:1) | ||
| H: 13.06.2021 12:00 | R: 19.06.2021 18:00 | Sieger: Málaga CF | ||||
| H | Real Madrid | - | Atlético Madrid | 2:1 (0:1) | ||
| R | Atlético Madrid | - | Real Madrid | 1:2 (0:1) | ||
| H: 13.06.2021 19:00 | R: 20.06.2021 20:00 | Sieger: Real Madrid | ||||
| H | Levante UD | - | FC Barcelona | 1:1 (0:1) | ||
| R | FC Barcelona | - | Levante UD | 2:1 (0:0) | ||
| H: 16.06.2021 18:00 | R: 20.06.2021 19:00 | Sieger: FC Barcelona | ||||
