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| 07.05.2016 | 18:00 | UD Almería B | - | Real Betis B | 0:1 (0:1) | |
| 18:00 | Sevilla Atlético | - | Mérida AD | 1:2 (0:2) | ||
| 18:00 | RB Linense | - | FC Jumilla | 3:1 (0:0) | ||
| 18:00 | Cádiz CF | - | UCAM Murcia CF | 0:2 (0:1) | ||
| 18:00 | Linares Deportivo | - | Real Jaén | 1:0 (1:0) | ||
| 18:00 | CD San Roque | - | Recreativo Huelva | 1:1 (0:0) | ||
| 18:00 | Real Murcia | - | Granada CF B | 3:4 (1:2) | ||
| 18:00 | La Hoya Lorca CF | - | Algeciras CF | 1:1 (0:0) | ||
| 18:00 | CF Villanovense | - | Marbella FC | 4:2 (1:1) | ||
| 08.05.2016 | 12:00 | UD Melilla | - | FC Cartagena | 1:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
UCAM Murcia CF | 37 | 21 | 11 | 5 | 43:16 | 27 | 74 |
| 2 |
|
Real Murcia | 37 | 20 | 8 | 9 | 54:29 | 25 | 68 |
| 3 |
|
Sevilla Atlético | 37 | 17 | 16 | 4 | 53:31 | 22 | 67 |
| 4 |
|
Cádiz CF | 37 | 16 | 12 | 9 | 52:31 | 21 | 60 |
| 5 |
|
Granada CF B | 37 | 14 | 13 | 10 | 52:40 | 12 | 55 |
| 6 |
|
La Hoya Lorca CF | 37 | 14 | 13 | 10 | 42:40 | 2 | 55 |
| 7 |
|
FC Cartagena | 37 | 12 | 16 | 9 | 39:34 | 5 | 52 |
| 8 |
|
Mérida AD | 37 | 12 | 15 | 10 | 36:38 | -2 | 51 |
| 9 |
|
UD Melilla | 37 | 12 | 13 | 12 | 34:40 | -6 | 49 |
| 10 |
|
Real Jaén | 37 | 14 | 6 | 17 | 46:36 | 10 | 48 |
| 11 |
|
RB Linense | 37 | 13 | 9 | 15 | 46:48 | -2 | 48 |
| 12 |
|
CF Villanovense | 37 | 13 | 8 | 16 | 48:52 | -4 | 47 |
| 13 |
|
Recreativo Huelva | 37 | 11 | 11 | 15 | 27:38 | -11 | 44 |
| 14 |
|
Marbella FC | 37 | 9 | 17 | 11 | 45:46 | -1 | 44 |
| 15 |
|
FC Jumilla | 37 | 11 | 9 | 17 | 36:57 | -21 | 42 |
| 16 |
|
Linares Deportivo | 37 | 9 | 15 | 13 | 39:46 | -7 | 42 |
| 17 |
|
Algeciras CF | 37 | 11 | 8 | 18 | 27:46 | -19 | 41 |
| 18 |
|
Real Betis B | 37 | 9 | 11 | 17 | 43:52 | -9 | 38 |
| 19 |
|
CD San Roque | 37 | 6 | 20 | 11 | 41:54 | -13 | 38 |
| 20 |
|
UD Almería B | 37 | 6 | 9 | 22 | 23:52 | -29 | 27 |
| Playoffs | |
| Playoffs | |
| Relegation | |
| Abstieg |
