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| 19.02.2021 | 21:00 | SD Ponferradina | - | CD Mirandés | 1:0 (0:0) | |
| 20.02.2021 | 16:00 | Espanyol Barcelona | - | CE Sabadell | 1:0 (0:0) | |
| 18:15 | Albacete | - | Sporting Gijón | 0:1 (0:1) | ||
| 20:30 | UD Las Palmas | - | FC Cartagena | 2:0 (2:0) | ||
| 21.02.2021 | 14:00 | CD Leganés | - | CD Tenerife | 1:0 (0:0) | |
| 16:00 | RCD Mallorca | - | UD Almería | 2:0 (1:0) | ||
| 18:15 | Girona FC | - | CD Castellón | 2:1 (2:0) | ||
| 20:30 | CD Lugo | - | UD Logroñés | 1:1 (0:0) | ||
| 21:00 | Málaga CF | - | Rayo Vallecano | 2:0 (2:0) | ||
| 22.02.2021 | 19:00 | CF Fuenlabrada | - | Real Oviedo | 2:2 (0:1) | |
| 21:00 | Real Zaragoza | - | AD Alcorcón | 0:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RCD Mallorca | 26 | 16 | 6 | 4 | 36:13 | 23 | 54 |
| 2 |
|
Espanyol Barcelona | 26 | 16 | 4 | 6 | 38:16 | 22 | 52 |
| 3 |
|
CD Leganés | 26 | 15 | 4 | 7 | 31:20 | 11 | 49 |
| 4 |
|
UD Almería | 26 | 15 | 4 | 7 | 38:24 | 14 | 49 |
| 5 |
|
Sporting Gijón | 26 | 13 | 7 | 6 | 27:17 | 10 | 46 |
| 6 |
|
Rayo Vallecano | 26 | 12 | 5 | 9 | 30:25 | 5 | 41 |
| 7 |
|
SD Ponferradina | 26 | 12 | 4 | 10 | 27:27 | 0 | 40 |
| 8 |
|
CD Mirandés | 26 | 10 | 7 | 9 | 26:22 | 4 | 37 |
| 9 |
|
Girona FC | 26 | 10 | 7 | 9 | 22:24 | -2 | 37 |
| 10 |
|
UD Las Palmas | 26 | 9 | 8 | 9 | 27:32 | -5 | 35 |
| 11 |
|
CF Fuenlabrada | 26 | 7 | 13 | 6 | 28:28 | 0 | 34 |
| 12 |
|
Málaga CF | 26 | 9 | 7 | 10 | 24:32 | -8 | 34 |
| 13 |
|
CD Tenerife | 26 | 9 | 6 | 11 | 22:24 | -2 | 33 |
| 14 |
|
CD Lugo | 26 | 8 | 9 | 9 | 26:27 | -1 | 33 |
| 15 |
|
Real Oviedo | 26 | 7 | 11 | 8 | 30:28 | 2 | 32 |
| 16 |
|
UD Logroñés | 26 | 8 | 6 | 12 | 19:32 | -13 | 30 |
| 17 |
|
Real Zaragoza | 26 | 7 | 6 | 13 | 21:25 | -4 | 27 |
| 18 |
|
CE Sabadell | 26 | 6 | 8 | 12 | 23:30 | -7 | 26 |
| 19 |
|
AD Alcorcón | 26 | 7 | 5 | 14 | 15:26 | -11 | 26 |
| 20 |
|
FC Cartagena | 26 | 6 | 7 | 13 | 27:37 | -10 | 25 |
| 21 |
|
Albacete | 26 | 6 | 6 | 14 | 17:32 | -15 | 24 |
| 22 |
|
CD Castellón | 26 | 6 | 4 | 16 | 23:36 | -13 | 22 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
