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| H | Manchester United | - | AS Roma | 6:2 (1:2) | ||
| R | AS Roma | - | Manchester United | 3:2 (0:1) | ||
| H: 29.04.2021 21:00 | R: 06.05.2021 21:00 | Sieger: Manchester United | ||||
| H | Villarreal CF | - | Arsenal FC | 2:1 (2:0) | ||
| R | Arsenal FC | - | Villarreal CF | 0:0 (0:0) | ||
| H: 29.04.2021 21:00 | R: 06.05.2021 21:00 | Sieger: Villarreal CF | ||||
