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| 08.01.2022 | 15:00 | Havre AC | - | FC Sochaux | 0:1 (0:0) | |
| 19:00 | Dijon FCO | - | Nîmes Olympique | 1:2 (0:2) | ||
| 19:00 | Pau FC | - | Rodez AF | 4:0 (0:0) | ||
| 19:00 | Valenciennes FC | - | EA Guingamp | 1:1 (1:0) | ||
| 19:00 | Grenoble Foot 38 | - | AJ Auxerre | 0:1 (0:1) | ||
| 19:00 | SC Bastia | - | US Quevilly-Rouen | 3:0 (1:0) | ||
| 19.01.2022 | 19:00 | Toulouse FC | - | AS Nancy Lorraine | 4:0 (2:0) | |
| 19:00 | Amiens SC | - | AC Ajaccio | 0:1 (0:1) | ||
| 28.01.2022 | 19:00 | SM Caen | - | Chamois Niortais | 0:2 (0:1) | |
| 19:00 | USL Dunkerque | - | Paris FC | 1:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
AC Ajaccio | 20 | 12 | 5 | 3 | 21:8 | 13 | 41 |
| 2 |
|
Toulouse FC | 20 | 11 | 7 | 2 | 44:18 | 26 | 40 |
| 3 |
|
Paris FC | 20 | 11 | 4 | 5 | 26:17 | 9 | 37 |
| 4 |
|
AJ Auxerre | 20 | 10 | 6 | 4 | 33:23 | 10 | 36 |
| 5 |
|
FC Sochaux | 20 | 10 | 6 | 4 | 21:16 | 5 | 36 |
| 6 |
|
Havre AC | 20 | 8 | 8 | 4 | 20:14 | 6 | 32 |
| 7 |
|
Chamois Niortais | 20 | 9 | 4 | 7 | 25:21 | 4 | 31 |
| 8 |
|
Pau FC | 20 | 8 | 3 | 9 | 23:23 | 0 | 27 |
| 9 |
|
Rodez AF | 20 | 7 | 6 | 7 | 20:21 | -1 | 27 |
| 10 |
|
Nîmes Olympique | 20 | 7 | 5 | 8 | 24:25 | -1 | 26 |
| 11 |
|
EA Guingamp | 20 | 6 | 7 | 7 | 24:28 | -4 | 25 |
| 12 |
|
US Quevilly-Rouen | 20 | 6 | 6 | 8 | 20:28 | -8 | 24 |
| 13 |
|
SC Bastia | 20 | 5 | 8 | 7 | 19:19 | 0 | 23 |
| 14 |
|
Dijon FCO | 20 | 7 | 2 | 11 | 25:29 | -4 | 23 |
| 15 |
|
SM Caen | 20 | 5 | 7 | 8 | 22:23 | -1 | 22 |
| 16 |
|
Valenciennes FC | 20 | 5 | 7 | 8 | 16:28 | -12 | 22 |
| 17 |
|
Amiens SC | 20 | 4 | 9 | 7 | 22:20 | 2 | 21 |
| 18 |
|
Grenoble Foot 38 | 20 | 6 | 3 | 11 | 17:27 | -10 | 21 |
| 19 |
|
USL Dunkerque | 20 | 4 | 5 | 11 | 16:27 | -11 | 17 |
| 20 |
|
AS Nancy Lorraine | 20 | 2 | 6 | 12 | 14:37 | -23 | 12 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
