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| 16.05.2021 | 11:00 | 1. FFC 08 Niederkirchen | - | Bayern München II | 0:5 (0:3) | |
| 11:00 | FC Ingolstadt 04 | - | Eintracht Frankfurt II | 2:0 (2:0) | ||
| 14:00 | 1. FC Saarbrücken | - | 1899 Hoffenheim II | 1:3 (0:1) | ||
| 14:00 | SG 99 Andernach | - | Würzburger Kickers | 3:1 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Köln | 13 | 12 | 1 | 0 | 37:9 | 28 | 37 |
| 2 |
|
SG 99 Andernach | 14 | 9 | 0 | 5 | 34:19 | 15 | 27 |
| 3 |
|
FC Ingolstadt 04 | 14 | 6 | 5 | 3 | 27:20 | 7 | 23 |
| 4 |
|
Bayern München II | 13 | 6 | 3 | 4 | 24:17 | 7 | 21 |
| 5 |
|
1899 Hoffenheim II | 13 | 4 | 5 | 4 | 24:19 | 5 | 17 |
| 6 |
|
Eintracht Frankfurt II | 13 | 5 | 1 | 7 | 19:19 | 0 | 16 |
| 7 |
|
1. FC Saarbrücken | 14 | 3 | 5 | 6 | 22:33 | -11 | 14 |
| 8 |
|
Würzburger Kickers | 13 | 3 | 2 | 8 | 17:26 | -9 | 11 |
| 9 |
|
1. FFC 08 Niederkirchen | 13 | 0 | 2 | 11 | 3:45 | -42 | 2 |
| Aufstieg | |
| Relegation | |
| Abstieg |
