 |
 |
|
|
| 14.12.2021 | 16:15 | Asteras Tripolis | - | Panetolikos | 1:0 (0:0) | |
| 15.12.2021 | 16:15 | Lamia | - | Volos NFC | 2:2 (0:1) | |
| 16:15 | PAS Giannina | - | PAOK Saloniki | 0:4 (0:1) | ||
| 18:30 | Atromitos | - | Olympiakos Piraeus | 0:3 (0:1) | ||
| 16.12.2021 | 16:00 | OFI Heraklion | - | Aris Saloniki | 1:1 (1:0) | |
| 18:30 | Ionikos Nikea | - | AEK Athen | 0:1 (0:1) | ||
| 16.02.2022 | 17:30 | Apollon Smyrnis | - | Panathinaikos | 0:3 (0:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiakos Piraeus | 14 | 12 | 2 | 0 | 27:9 | 18 | 38 |
| 2 |
|
AEK Athen | 14 | 9 | 3 | 2 | 26:14 | 12 | 30 |
| 3 |
|
PAOK Saloniki | 14 | 8 | 1 | 5 | 28:18 | 10 | 25 |
| 4 |
|
Aris Saloniki | 14 | 7 | 3 | 4 | 16:13 | 3 | 24 |
| 5 |
|
Panathinaikos | 14 | 7 | 2 | 5 | 25:11 | 14 | 23 |
| 6 |
|
OFI Heraklion | 14 | 5 | 7 | 2 | 18:13 | 5 | 22 |
| 7 |
|
PAS Giannina | 14 | 6 | 4 | 4 | 19:14 | 5 | 22 |
| 8 |
|
Asteras Tripolis | 14 | 4 | 5 | 5 | 13:12 | 1 | 17 |
| 9 |
|
Volos NFC | 14 | 4 | 3 | 7 | 24:29 | -5 | 15 |
| 10 |
|
Ionikos Nikea | 14 | 3 | 5 | 6 | 13:19 | -6 | 14 |
| 11 |
|
Panetolikos | 14 | 3 | 3 | 8 | 14:26 | -12 | 12 |
| 12 |
|
Lamia | 14 | 2 | 5 | 7 | 13:19 | -6 | 11 |
| 13 |
|
Atromitos | 14 | 2 | 3 | 9 | 13:30 | -17 | 9 |
| 14 |
|
Apollon Smyrnis | 14 | 1 | 4 | 9 | 7:29 | -22 | 7 |
| Playoffs | |
| Relegation |
