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| H | Torino FC | - | Sampdoria | 0:2 (0:0) | ||
| R | Sampdoria | - | Torino FC | 1:2 (0:0) | ||
| H: 19.11.2004 15:00 | R: 12.01.2005 20:30 | Sieger: Sampdoria | ||||
| H | AS Roma | - | AC Siena | 1:2 (0:1) | ||
| R | AC Siena | - | AS Roma | 1:5 (1:2) | ||
| H: 19.11.2004 17:00 | R: 13.01.2005 17:30 | Sieger: AS Roma | ||||
| H | Atalanta | - | Juventus | 2:0 (0:0) | ||
| R | Juventus | - | Atalanta | 3:3 (2:2) | ||
| H: 19.11.2004 21:00 | R: 13.01.2005 21:00 | Sieger: Atalanta | ||||
| H | US Lecce | - | Udinese Calcio | 4:5 (3:2) | ||
| R | Udinese Calcio | - | US Lecce | 3:4 (1:1) | ||
| H: 20.11.2004 15:00 | R: 13.01.2005 15:00 | Sieger: Udinese Calcio | ||||
| H | ACF Fiorentina | - | Parma FC | 2:0 (1:0) | ||
| R | Parma FC | - | ACF Fiorentina | 0:3 (0:0) | ||
| H: 20.11.2004 17:00 | R: 12.01.2005 15:00 | Sieger: ACF Fiorentina | ||||
| H | US Palermo | - | AC Milan | 1:2 (0:0) | ||
| R | AC Milan | - | US Palermo | 2:0 (1:0) | ||
| H: 20.11.2004 21:00 | R: 12.01.2005 21:00 | Sieger: AC Milan | ||||
| H | Cagliari Calcio | - | Lazio Roma | 2:1 (1:0) | ||
| R | Lazio Roma | - | Cagliari Calcio | 3:2 (1:0, 2:1) n.V. | ||
| H: 21.11.2004 16:00 | R: 13.01.2005 15:00 | Sieger: Cagliari Calcio | ||||
| H | Inter | - | Bologna FC | 3:1 (1:1) | ||
| R | Bologna FC | - | Inter | 1:3 (1:0) | ||
| H: 21.11.2004 21:00 | R: 12.01.2005 17:30 | Sieger: Inter | ||||
