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| H | AC Milan | - | Brescia Calcio | 3:1 (2:0) | ||
| R | Brescia Calcio | - | AC Milan | 3:4 (1:2) | ||
| H: 29.11.2005 21:05 | R: 11.01.2006 21:00 | Sieger: AC Milan | ||||
| H | Atalanta | - | Udinese Calcio | 1:0 (0:0) | ||
| R | Udinese Calcio | - | Atalanta | 3:1 (1:0) | ||
| H: 30.11.2005 18:05 | R: 11.01.2006 17:30 | Sieger: Udinese Calcio | ||||
| H | Parma FC | - | Inter | 0:1 (0:0) | ||
| R | Inter | - | Parma FC | 0:0 (0:0) | ||
| H: 30.11.2005 21:05 | R: 12.01.2006 21:00 | Sieger: Inter | ||||
| H | ACF Fiorentina | - | Juventus | 2:2 (1:0) | ||
| R | Juventus | - | ACF Fiorentina | 4:1 (3:0) | ||
| H: 01.12.2005 21:05 | R: 10.01.2006 21:00 | Sieger: Juventus | ||||
| H | AS Bari | - | US Palermo | 0:0 (0:0) | ||
| R | US Palermo | - | AS Bari | 5:4 (2:1) | ||
| H: 07.12.2005 18:00 | R: 10.01.2006 15:00 | Sieger: US Palermo | ||||
| H | Lazio Roma | - | AS Cittadella | 2:0 (1:0) | ||
| R | AS Cittadella | - | Lazio Roma | 0:0 (0:0) | ||
| H: 08.12.2005 15:00 | R: 12.01.2006 15:30 | Sieger: Lazio Roma | ||||
| H | SSC Napoli | - | AS Roma | 0:3 (0:2) | ||
| R | AS Roma | - | SSC Napoli | 2:1 (2:0) | ||
| H: 08.12.2005 15:00 | R: 11.01.2006 17:00 | Sieger: AS Roma | ||||
| H | Cagliari Calcio | - | Sampdoria | 1:1 (0:0) | ||
| R | Sampdoria | - | Cagliari Calcio | 2:1 (0:0) | ||
| H: 08.12.2005 18:00 | R: 11.01.2006 20:30 | Sieger: Sampdoria | ||||
