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| 04.12.2022 | 14:30 | ACR Messina | - | AZ Picerno | 0:1 (0:1) | |
| 14:30 | Gelbison | - | Latina Calcio | 0:0 (0:0) | ||
| 14:30 | Monterosi FC | - | Viterbese | 2:1 (0:0) | ||
| 14:30 | US Catanzaro | - | Virtus Francavilla | 4:1 (2:0) | ||
| 17:30 | Audace Cerignola | - | FC Crotone | 0:1 (0:0) | ||
| 17:30 | Giugliano | - | Foggia Calcio | 3:2 (1:0) | ||
| 17:30 | Fidelis Andria | - | SS Juve Stabia | 0:1 (0:0) | ||
| 17:30 | SS Monopoli 1966 | - | Potenza | 1:2 (0:2) | ||
| 17:30 | FC Turris | - | US Avellino | 1:3 (1:2) | ||
| 05.12.2022 | 20:30 | Delfino Pescara | - | Taranto FC | 0:2 (0:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
US Catanzaro | 17 | 15 | 2 | 0 | 49:7 | 42 | 47 |
| 2 |
|
FC Crotone | 17 | 13 | 2 | 2 | 29:12 | 17 | 41 |
| 3 |
|
Delfino Pescara | 17 | 11 | 2 | 4 | 29:18 | 11 | 35 |
| 4 |
|
Giugliano | 17 | 7 | 5 | 5 | 23:20 | 3 | 26 |
| 5 |
|
SS Juve Stabia | 17 | 7 | 5 | 5 | 13:11 | 2 | 26 |
| 6 |
|
Audace Cerignola | 17 | 6 | 6 | 5 | 19:18 | 1 | 24 |
| 7 |
|
Gelbison | 17 | 5 | 7 | 5 | 12:12 | 0 | 22 |
| 8 |
|
SS Monopoli 1966 | 17 | 6 | 4 | 7 | 18:19 | -1 | 22 |
| 9 |
|
Foggia Calcio | 17 | 6 | 4 | 7 | 19:25 | -6 | 22 |
| 10 |
|
AZ Picerno | 17 | 5 | 6 | 6 | 16:18 | -2 | 21 |
| 11 |
|
Latina Calcio | 17 | 5 | 6 | 6 | 17:23 | -6 | 21 |
| 12 |
|
US Avellino | 17 | 5 | 5 | 7 | 20:19 | 1 | 20 |
| 13 |
|
Potenza | 17 | 3 | 11 | 3 | 21:22 | -1 | 20 |
| 14 |
|
Taranto FC | 17 | 6 | 2 | 9 | 16:27 | -11 | 20 |
| 15 |
|
Virtus Francavilla | 17 | 5 | 4 | 8 | 19:26 | -7 | 19 |
| 16 |
|
FC Turris | 17 | 5 | 4 | 8 | 23:31 | -8 | 19 |
| 17 |
|
Monterosi FC | 17 | 5 | 5 | 7 | 24:24 | 0 | 18 |
| 18 |
|
Fidelis Andria | 17 | 3 | 6 | 8 | 15:23 | -8 | 15 |
| 19 |
|
ACR Messina | 17 | 3 | 2 | 12 | 13:28 | -15 | 11 |
| 20 |
|
Viterbese | 17 | 2 | 6 | 9 | 16:28 | -12 | 10 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
