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| 18.04.2021 | 15:00 | ACN Siena 1904 | - | Badesse Calcio | 2:2 | |
| 15:00 | Virtus Flaminia | - | ASD Cannara | 1:1 | ||
| 15:00 | Foligno Calcio | - | SC Trestina | 1:2 | ||
| 15:00 | Ostia Mare | - | Montespaccato | 3:1 | ||
| 15:00 | US Pianese | - | San Donato Tavarnelle | 4:2 | ||
| 15:00 | AC Sangiovannese | - | Scandicci Calcio | 2:1 | ||
| 15:00 | SSD Tiferno Lerchi | - | Grassina | 1:2 | ||
| 15:00 | ASD Trastevere | - | Aquila Montevarchi | 2:2 | ||
| 15:00 | UC Sinalunghese | - | Follonica Gavorrano | 1:1 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Aquila Montevarchi | 27 | 16 | 6 | 5 | 50:25 | 25 | 54 |
| 2 |
|
ASD Trastevere | 27 | 16 | 6 | 5 | 48:25 | 23 | 54 |
| 3 |
|
SC Trestina | 27 | 12 | 8 | 7 | 39:27 | 12 | 44 |
| 4 |
|
ACN Siena 1904 | 27 | 12 | 7 | 8 | 34:30 | 4 | 43 |
| 5 |
|
Follonica Gavorrano | 27 | 11 | 7 | 9 | 36:29 | 7 | 40 |
| 6 |
|
US Pianese | 27 | 10 | 10 | 7 | 32:26 | 6 | 40 |
| 7 |
|
SSD Tiferno Lerchi | 27 | 11 | 7 | 9 | 37:36 | 1 | 40 |
| 8 |
|
San Donato Tavarnelle | 27 | 10 | 10 | 7 | 34:33 | 1 | 40 |
| 9 |
|
AC Sangiovannese | 27 | 11 | 6 | 10 | 36:34 | 2 | 39 |
| 10 |
|
ASD Cannara | 27 | 10 | 9 | 8 | 34:35 | -1 | 39 |
| 11 |
|
Montespaccato | 27 | 10 | 5 | 12 | 30:34 | -4 | 35 |
| 12 |
|
Ostia Mare | 27 | 8 | 9 | 10 | 40:42 | -2 | 33 |
| 13 |
|
Badesse Calcio | 27 | 8 | 8 | 11 | 38:39 | -1 | 32 |
| 14 |
|
Virtus Flaminia | 27 | 7 | 9 | 11 | 32:44 | -12 | 30 |
| 15 |
|
Foligno Calcio | 27 | 7 | 7 | 13 | 24:36 | -12 | 28 |
| 16 |
|
Scandicci Calcio | 27 | 6 | 6 | 15 | 27:41 | -14 | 22 |
| 17 |
|
Grassina | 27 | 4 | 10 | 13 | 23:39 | -16 | 22 |
| 18 |
|
UC Sinalunghese | 27 | 4 | 10 | 13 | 22:41 | -19 | 22 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
