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| 26.02.2023 | 14:30 | ASG Nocerina | - | SS Barletta Calcio | 0:1 (0:1) | |
| 14:30 | US Bitonto | - | Sporting Fulgor Molfetta | 3:1 (1:1) | ||
| 14:30 | Casarano | - | Matera Calcio | 2:1 (1:1) | ||
| 14:30 | Cavese | - | Gladiator | 5:3 (3:1) | ||
| 14:30 | FC Francavilla | - | ACD Nardò | 2:1 (1:0) | ||
| 14:30 | Lavello | - | Afragolese | 1:2 (0:2) | ||
| 15:00 | Martina | - | Puteolana Internapoli | 2:1 (0:1) | ||
| 15:00 | Brindisi | - | Team Altamura | 1:1 (1:0) | ||
| 15:00 | FBC Gravina | - | Città di Fasano | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Cavese | 25 | 14 | 8 | 3 | 43:25 | 18 | 50 |
| 2 |
|
SS Barletta Calcio | 25 | 13 | 9 | 3 | 28:17 | 11 | 48 |
| 3 |
|
ACD Nardò | 25 | 12 | 10 | 3 | 30:15 | 15 | 46 |
| 4 |
|
Casarano | 25 | 11 | 12 | 2 | 37:23 | 14 | 45 |
| 5 |
|
Brindisi | 25 | 12 | 8 | 5 | 39:24 | 15 | 44 |
| 6 |
|
Team Altamura | 25 | 10 | 10 | 5 | 36:26 | 10 | 40 |
| 7 |
|
Matera Calcio | 25 | 10 | 7 | 8 | 42:36 | 6 | 37 |
| 8 |
|
Città di Fasano | 25 | 9 | 9 | 7 | 35:28 | 7 | 36 |
| 9 |
|
US Bitonto | 25 | 10 | 6 | 9 | 37:36 | 1 | 36 |
| 10 |
|
Martina | 25 | 9 | 8 | 8 | 32:33 | -1 | 35 |
| 11 |
|
Afragolese | 25 | 5 | 11 | 9 | 32:35 | -3 | 26 |
| 12 |
|
ASG Nocerina | 25 | 6 | 8 | 11 | 26:32 | -6 | 26 |
| 13 |
|
Gladiator | 25 | 6 | 8 | 11 | 32:44 | -12 | 26 |
| 14 |
|
FC Francavilla | 25 | 6 | 7 | 12 | 29:35 | -6 | 25 |
| 15 |
|
Sporting Fulgor Molfetta | 25 | 5 | 8 | 12 | 33:41 | -8 | 23 |
| 16 |
|
FBC Gravina | 25 | 3 | 12 | 10 | 19:32 | -13 | 21 |
| 17 |
|
Lavello | 25 | 5 | 4 | 16 | 18:48 | -30 | 19 |
| 18 |
|
Puteolana Internapoli | 25 | 2 | 9 | 14 | 26:44 | -18 | 15 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
