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| H | Atlas Guadalajara | - | CF Monterrey | 0:0 (0:0) | ||
| R | CF Monterrey | - | Atlas Guadalajara | 1:0 (1:0) | ||
| H: 14.11.2019 22:45 | R: 19.11.2019 02:00 | Sieger: CF Monterrey | ||||
| H | Club Tijuana | - | UANL Tigres | 0:0 (0:0) | ||
| R | UANL Tigres | - | Club Tijuana | 3:0 (0:0) | ||
| H: 15.11.2019 04:00 | R: 18.11.2019 02:00 | Sieger: UANL Tigres | ||||
| H | Deportivo Toluca | - | CF Pachuca | 1:4 (1:2) | ||
| R | CF Pachuca | - | Deportivo Toluca | 1:2 (1:0) | ||
| H: 16.11.2019 00:00 | R: 19.11.2019 04:00 | Sieger: CF Pachuca | ||||
| H | Deportivo Guadalajara | - | CF América | 0:2 (0:2) | ||
| R | CF América | - | Deportivo Guadalajara | 1:0 (1:0) | ||
| H: 16.11.2019 04:06 | R: 18.11.2019 22:45 | Sieger: CF América | ||||
