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| H | Correcaminos UAT | - | Club Necaxa | 0:1 | ||
| R | Club Necaxa | - | Correcaminos UAT | 1:1 | ||
| H: 21.04.2016 01:30 | R: 24.04.2016 02:45 | Sieger: Club Necaxa | ||||
| H | Atlante | - | Club Celaya | 0:1 | ||
| R | Club Celaya | - | Atlante | 0:2 | ||
| H: 21.04.2016 02:45 | R: 24.04.2016 04:15 | Sieger: Atlante | ||||
| H | Mineros de Zacatecas | - | Cafetaleros de Tapachula | 2:1 | ||
| R | Cafetaleros de Tapachula | - | Mineros de Zacatecas | 1:1 | ||
| H: 21.04.2016 04:15 | R: 24.04.2016 01:00 | Sieger: Mineros de Zacatecas | ||||
