 |
 |
|
|
| H | Atlante | - | Club Celaya | 2:0 (2:0) | ||
| R | Club Celaya | - | Atlante | 3:3 (1:2) | ||
| H: 27.04.2021 19:00 | R: 01.05.2021 00:00 | Sieger: Atlante | ||||
| H | Tepatitlán | - | Cimarrones de Sonora | 2:0 (0:0) | ||
| R | Cimarrones de Sonora | - | Tepatitlán | 1:4 (1:1) | ||
| H: 29.04.2021 00:00 | R: 02.05.2021 05:00 | Sieger: Tepatitlán | ||||
| H | Tapatío | - | Mineros de Zacatecas | 0:1 (0:0) | ||
| R | Mineros de Zacatecas | - | Tapatío | 2:1 (0:1) | ||
| H: 30.04.2021 00:00 | R: 03.05.2021 00:00 | Sieger: Mineros de Zacatecas | ||||
