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| H | Atlas Guadalajara | - | Puebla FC | 1:2 (1:2) | ||
| R | Puebla FC | - | Atlas Guadalajara | 3:3 (1:1) | ||
| H: 25.04.2001 | R: 28.04.2001 | Sieger: Puebla FC | ||||
| H | Monarcas Morelia | - | UAG Tecos | 3:3 (1:2) | ||
| R | UAG Tecos | - | Monarcas Morelia | 1:1 (0:0) | ||
| H: 26.04.2001 | R: 29.04.2001 | Sieger: UAG Tecos | ||||
