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| H | CF Monterrey | - | CF América | 2:2 (1:0) | ||
| R | CF América | - | CF Monterrey | 2:1 (0:0) | ||
| H: 16.05.2013 04:00 | R: 19.05.2013 00:00 | Sieger: CF América | ||||
| H | Santos Laguna | - | Cruz Azul | 0:3 (0:2) | ||
| R | Cruz Azul | - | Santos Laguna | 2:1 (2:1) | ||
| H: 17.05.2013 04:00 | R: 20.05.2013 03:00 | Sieger: Cruz Azul | ||||
