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| 06.01.2023 | 20:00 | Jong Ajax | - | FC Eindhoven | 1:1 (0:0) | |
| 20:00 | AZ Alkmaar (J) | - | Heracles Almelo | 1:1 (0:0) | ||
| 20:00 | FC Den Bosch | - | FC Utrecht (J) | 1:4 (0:1) | ||
| 20:00 | FC Dordrecht | - | ADO Den Haag | 0:1 (0:1) | ||
| 20:00 | MVV | - | De Graafschap | 2:2 (1:1) | ||
| 20:00 | NAC Breda | - | Jong PSV | 2:1 (2:1) | ||
| 20:00 | TOP Oss | - | Telstar | 2:1 (1:1) | ||
| 20:00 | PEC Zwolle | - | Almere City FC | 3:2 (1:1) | ||
| 20:00 | VVV-Venlo | - | Helmond Sport | 1:1 (1:0) | ||
| 20:00 | Willem II | - | Roda JC Kerkrade | 1:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Heracles Almelo | 19 | 14 | 2 | 3 | 56:23 | 33 | 44 |
| 2 |
|
PEC Zwolle | 19 | 14 | 2 | 3 | 46:22 | 24 | 44 |
| 3 |
|
MVV | 19 | 10 | 4 | 5 | 36:31 | 5 | 34 |
| 4 |
|
FC Eindhoven | 19 | 9 | 6 | 4 | 31:24 | 7 | 33 |
| 5 |
|
Almere City FC | 19 | 10 | 2 | 7 | 30:25 | 5 | 32 |
| 6 |
|
VVV-Venlo | 19 | 9 | 5 | 5 | 29:27 | 2 | 32 |
| 7 |
|
AZ Alkmaar (J) | 19 | 9 | 4 | 6 | 33:24 | 9 | 31 |
| 8 |
|
Willem II | 19 | 8 | 6 | 5 | 28:21 | 7 | 30 |
| 9 |
|
Telstar | 19 | 6 | 7 | 6 | 22:28 | -6 | 25 |
| 10 |
|
Jong PSV | 19 | 6 | 6 | 7 | 31:31 | 0 | 24 |
| 11 |
|
NAC Breda | 19 | 7 | 3 | 9 | 25:32 | -7 | 24 |
| 12 |
|
Roda JC Kerkrade | 19 | 7 | 3 | 9 | 28:28 | 0 | 24 |
| 13 |
|
Jong Ajax | 19 | 5 | 8 | 6 | 34:33 | 1 | 23 |
| 14 |
|
De Graafschap | 19 | 6 | 4 | 9 | 28:32 | -4 | 22 |
| 15 |
|
ADO Den Haag | 19 | 5 | 5 | 9 | 21:30 | -9 | 20 |
| 16 |
|
FC Den Bosch | 19 | 6 | 1 | 12 | 27:37 | -10 | 19 |
| 17 |
|
FC Dordrecht | 19 | 5 | 4 | 10 | 23:36 | -13 | 19 |
| 18 |
|
Helmond Sport | 19 | 6 | 1 | 12 | 15:32 | -17 | 19 |
| 19 |
|
TOP Oss | 19 | 5 | 2 | 12 | 19:33 | -14 | 17 |
| 20 |
|
FC Utrecht (J) | 19 | 4 | 3 | 12 | 19:32 | -13 | 15 |
| Aufstieg | |
| Playoffs |
