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| 30.10.2021 | 18:00 | Siegburger SV 04 | - | Spvg Wesseling-Urfeld | 4:0 (1:0) | |
| 31.10.2021 | 15:00 | Viktoria Arnoldsweiler | - | SV Breinig | 3:0 (1:0) | |
| 15:00 | Borussia Freialdenhoven | - | SV Deutz 05 | 3:1 (2:0) | ||
| 15:00 | SV Bergisch Gladbach 09 | - | FC Pesch 1956 | 3:2 (0:1) | ||
| 15:00 | SV 1914 Eilendorf | - | BC Viktoria Glesch-Paffendorf | 1:1 (1:0) | ||
| 15:00 | FC Hürth | - | Fortuna Köln II | 2:2 (1:2) | ||
| 15:30 | Blau-Weiß Friesdorf | - | VfL Alfter | 4:2 (2:1) | ||
| 15:30 | VfL 08 Vichttal | - | FC Hennef 05 | 1:1 (0:0) | ||
| 15:30 | SpVg Frechen 20 | - | 1. FC Düren | 3:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Düren | 13 | 10 | 2 | 1 | 42:11 | 31 | 32 |
| 2 |
|
FC Hennef 05 | 13 | 9 | 3 | 1 | 30:8 | 22 | 30 |
| 3 |
|
SpVg Frechen 20 | 13 | 9 | 2 | 2 | 29:10 | 19 | 29 |
| 4 |
|
SV Bergisch Gladbach 09 | 13 | 8 | 4 | 1 | 35:9 | 26 | 28 |
| 5 |
|
Siegburger SV 04 | 13 | 7 | 4 | 2 | 21:11 | 10 | 25 |
| 6 |
|
Borussia Freialdenhoven | 13 | 8 | 1 | 4 | 24:15 | 9 | 25 |
| 7 |
|
VfL Alfter | 13 | 6 | 3 | 4 | 22:22 | 0 | 21 |
| 8 |
|
FC Hürth | 13 | 6 | 2 | 5 | 22:26 | -4 | 20 |
| 9 |
|
Viktoria Arnoldsweiler | 13 | 6 | 1 | 6 | 24:21 | 3 | 19 |
| 10 |
|
FC Pesch 1956 | 13 | 4 | 6 | 3 | 25:15 | 10 | 18 |
| 11 |
|
BC Viktoria Glesch-Paffendorf | 13 | 5 | 3 | 5 | 19:16 | 3 | 18 |
| 12 |
|
VfL 08 Vichttal | 13 | 5 | 3 | 5 | 21:23 | -2 | 18 |
| 13 |
|
Blau-Weiß Friesdorf | 13 | 4 | 4 | 5 | 21:25 | -4 | 16 |
| 14 |
|
Spvg Wesseling-Urfeld | 13 | 3 | 0 | 10 | 13:39 | -26 | 9 |
| 15 |
|
SV Deutz 05 | 13 | 2 | 2 | 9 | 13:33 | -20 | 8 |
| 16 |
|
Fortuna Köln II | 13 | 1 | 3 | 9 | 11:29 | -18 | 6 |
| 17 |
|
SV 1914 Eilendorf | 13 | 1 | 2 | 10 | 9:33 | -24 | 5 |
| 18 |
|
SV Breinig | 13 | 0 | 1 | 12 | 8:43 | -35 | 1 |
| Playoffs | |
| Abstieg |
