 |
 |
|
|
| 08.05.2021 | 23:45 | Sportivo Luqueño | - | Guaraní | 1:2 (0:1) | |
| 09.05.2021 | 02:00 | Cerro Porteño | - | Club Nacional | 2:2 (2:0) | |
| 23:45 | Club Olimpia | - | Sol de América | 3:3 (1:1) | ||
| 23:45 | Libertad | - | 12 de Octubre de Itauguá | 3:1 (0:1) | ||
| 10.05.2021 | 02:00 | Guaireña FC | - | River Plate | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Libertad | 15 | 10 | 2 | 3 | 26:11 | 15 | 32 |
| 2 |
|
Club Olimpia | 15 | 8 | 3 | 4 | 27:19 | 8 | 27 |
| 3 |
|
Cerro Porteño | 15 | 8 | 3 | 4 | 23:18 | 5 | 27 |
| 4 |
|
Club Nacional | 15 | 7 | 5 | 3 | 22:15 | 7 | 26 |
| 5 |
|
Guaireña FC | 15 | 6 | 5 | 4 | 19:13 | 6 | 23 |
| 6 |
|
Guaraní | 15 | 6 | 3 | 6 | 21:21 | 0 | 21 |
| 7 |
|
12 de Octubre de Itauguá | 15 | 4 | 5 | 6 | 16:22 | -6 | 17 |
| 8 |
|
Sportivo Luqueño | 15 | 4 | 3 | 8 | 15:22 | -7 | 15 |
| 9 |
|
Sol de América | 15 | 2 | 4 | 9 | 16:25 | -9 | 10 |
| 10 |
|
River Plate | 15 | 1 | 5 | 9 | 10:29 | -19 | 8 |
| Copa Libertadores |
