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| 14.10.2021 | 12:00 | FC Vizela | - | FC Famalicão | 3:2 (3:1) | |
| 15.10.2021 | 12:00 | Rio Ave FC | - | Vitória Guimarães | 1:1 (0:1) | |
| 16.10.2021 | 12:00 | GD Estoril | - | Belenenses SAD | 2:0 (1:0) | |
| 12:00 | Portimonense SC | - | CS Marítimo | 2:1 (1:1) | ||
| 16:00 | Académica de Coimbra | - | Leixões SC | 0:1 (0:1) | ||
| 24.10.2021 | 14:00 | Sporting CP | - | SL Benfica | 1:3 (0:1) |
| 1 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Rio Ave FC | 6 | 4 | 2 | 0 | 6:2 | 4 | 14 |
| 2 |
|
Sporting Braga | 6 | 4 | 1 | 1 | 8:3 | 5 | 13 |
| 3 |
|
Leixões SC | 6 | 3 | 1 | 2 | 5:3 | 2 | 10 |
| 4 |
|
Vitória Guimarães | 6 | 2 | 2 | 2 | 10:7 | 3 | 8 |
| 5 |
|
FC Famalicão | 6 | 2 | 1 | 3 | 6:8 | -2 | 7 |
| 6 |
|
FC Vizela | 6 | 1 | 2 | 3 | 6:10 | -4 | 5 |
| 7 |
|
Académica de Coimbra | 6 | 0 | 1 | 5 | 3:11 | -8 | 1 |
| 2 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
GD Estoril | 6 | 5 | 1 | 0 | 11:2 | 9 | 16 |
| 2 |
|
SL Benfica | 6 | 3 | 2 | 1 | 8:5 | 3 | 11 |
| 3 |
|
Sporting CP | 6 | 3 | 1 | 2 | 11:9 | 2 | 10 |
| 4 |
|
Portimonense SC | 6 | 3 | 1 | 2 | 7:9 | -2 | 10 |
| 5 |
|
CS Marítimo | 6 | 3 | 0 | 3 | 11:8 | 3 | 9 |
| 6 |
|
Belenenses SAD | 6 | 1 | 0 | 5 | 7:16 | -9 | 3 |
| 7 |
|
SC Farense | 6 | 0 | 1 | 5 | 3:9 | -6 | 1 |
| Playoffs | |
| Relegation | |
| Playoffs | |
| Relegation |
