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| 27.03.2021 | 14:00 | Eintracht Stadtallendorf | - | FC-Astoria Walldorf | 0:6 (0:3) | |
| 14:00 | FC 08 Homburg | - | Rot-Weiß Koblenz | 2:1 (2:1) | ||
| 14:00 | Bayern Alzenau | - | Kickers Offenbach | 1:3 (1:1) | ||
| 14:00 | FC Gießen | - | Bahlinger SC | 1:1 (1:0) | ||
| 14:00 | FK Pirmasens | - | SV 07 Elversberg | 0:2 (0:0) | ||
| 14:00 | Hessen Kassel | - | FSV Frankfurt | 2:1 (2:0) | ||
| 14:00 | SC Freiburg II | - | 1899 Hoffenheim II | 2:0 (0:0) | ||
| 14:00 | SSV Ulm 1846 | - | SG Sonnenhof Großaspach | 1:1 (0:1) | ||
| 14:00 | TSV Schott Mainz | - | VfR Aalen | 1:1 (0:0) | ||
| 14:00 | TSV Steinbach Haiger | - | TSG Balingen | 1:1 (0:1) | ||
| 14:00 | VfB Stuttgart II | - | 1. FSV Mainz 05 II | 2:3 (1:1) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Freiburg II | 29 | 18 | 7 | 4 | 71:32 | 39 | 61 |
| 2 |
|
TSV Steinbach Haiger | 29 | 16 | 8 | 5 | 60:30 | 30 | 56 |
| 3 |
|
SSV Ulm 1846 | 29 | 16 | 8 | 5 | 53:25 | 28 | 56 |
| 4 |
|
SV 07 Elversberg | 29 | 15 | 10 | 4 | 66:30 | 36 | 55 |
| 5 |
|
Kickers Offenbach | 29 | 15 | 10 | 4 | 48:21 | 27 | 55 |
| 6 |
|
FSV Frankfurt | 29 | 16 | 6 | 7 | 41:30 | 11 | 54 |
| 7 |
|
VfB Stuttgart II | 29 | 13 | 6 | 10 | 57:36 | 21 | 45 |
| 8 |
|
FC 08 Homburg | 29 | 11 | 10 | 8 | 51:41 | 10 | 43 |
| 9 |
|
Bahlinger SC | 29 | 12 | 7 | 10 | 46:53 | -7 | 43 |
| 10 |
|
Rot-Weiß Koblenz | 29 | 11 | 6 | 12 | 35:39 | -4 | 39 |
| 11 |
|
TSG Balingen | 29 | 10 | 8 | 11 | 38:36 | 2 | 38 |
| 12 |
|
1. FSV Mainz 05 II | 29 | 10 | 8 | 11 | 39:45 | -6 | 38 |
| 13 |
|
VfR Aalen | 29 | 9 | 9 | 11 | 31:40 | -9 | 36 |
| 14 |
|
Hessen Kassel | 29 | 9 | 8 | 12 | 40:52 | -12 | 35 |
| 15 |
|
FK Pirmasens | 29 | 8 | 11 | 10 | 27:44 | -17 | 35 |
| 16 |
|
FC Gießen | 29 | 8 | 10 | 11 | 30:34 | -4 | 34 |
| 17 |
|
FC-Astoria Walldorf | 29 | 9 | 4 | 16 | 40:49 | -9 | 31 |
| 18 |
|
1899 Hoffenheim II | 29 | 8 | 7 | 14 | 35:51 | -16 | 31 |
| 19 |
|
SG Sonnenhof Großaspach | 29 | 7 | 9 | 13 | 36:51 | -15 | 30 |
| 20 |
|
TSV Schott Mainz | 29 | 7 | 5 | 17 | 36:70 | -34 | 26 |
| 21 |
|
Bayern Alzenau | 29 | 5 | 7 | 17 | 34:58 | -24 | 22 |
| 22 |
|
Eintracht Stadtallendorf | 29 | 1 | 6 | 22 | 22:69 | -47 | 9 |
| Aufstieg | |
| Abstieg |
