 |
 |
|
|
| 22.10.2021 | 17:00 | ŠKF Sereď | - | MŠK Žilina | 1:1 (1:1) | |
| 23.10.2021 | 18:00 | Zlaté Moravce | - | AS Trenčín | 0:1 (0:0) | |
| 18:00 | FK Senica | - | MFK Ružomberok | 0:2 (0:1) | ||
| 18:00 | FK Pohronie | - | Spartak Trnava | 0:2 (0:2) | ||
| 24.10.2021 | 15:00 | Slovan Bratislava | - | Tatran Liptovský Mikuláš | 4:0 (0:0) | |
| 17:00 | FC DAC 1904 | - | MFK Zemplín Michalovce | 1:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Bratislava | 12 | 9 | 2 | 1 | 32:8 | 24 | 29 |
| 2 |
|
Spartak Trnava | 12 | 8 | 2 | 2 | 20:7 | 13 | 26 |
| 3 |
|
MFK Ružomberok | 12 | 5 | 6 | 1 | 18:10 | 8 | 21 |
| 4 |
|
FC DAC 1904 | 12 | 6 | 3 | 3 | 19:15 | 4 | 21 |
| 5 |
|
AS Trenčín | 12 | 4 | 5 | 3 | 18:14 | 4 | 17 |
| 6 |
|
MFK Zemplín Michalovce | 12 | 5 | 2 | 5 | 14:14 | 0 | 17 |
| 7 |
|
MŠK Žilina | 12 | 4 | 3 | 5 | 16:15 | 1 | 15 |
| 8 |
|
FK Senica | 12 | 3 | 5 | 4 | 12:18 | -6 | 14 |
| 9 |
|
ŠKF Sereď | 12 | 3 | 4 | 5 | 11:15 | -4 | 13 |
| 10 |
|
Tatran Liptovský Mikuláš | 12 | 3 | 1 | 8 | 16:30 | -14 | 10 |
| 11 |
|
Zlaté Moravce | 12 | 1 | 4 | 7 | 12:25 | -13 | 7 |
| 12 |
|
FK Pohronie | 12 | 1 | 3 | 8 | 10:27 | -17 | 6 |
| Playoffs | |
| Relegation |
