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| 03.04.2021 | 12:30 | Kayserispor | - | Göztepe | 1:1 (1:0) | |
| 15:00 | Çaykur Rizespor | - | Fatih Karagümrük SK | 0:0 (0:0) | ||
| 15:00 | Sivasspor | - | Trabzonspor | 0:0 (0:0) | ||
| 18:00 | Hatayspor | - | Galatasaray | 3:0 (2:0) | ||
| 04.04.2021 | 12:30 | BB Erzurumspor | - | Konyaspor | 1:2 (1:2) | |
| 15:00 | Alanyaspor | - | Gençlerbirliği | 1:2 (1:1) | ||
| 15:00 | MKE Ankaragücü | - | Antalyaspor | 1:0 (0:0) | ||
| 15:00 | İstanbul Başakşehir | - | Yeni Malatyaspor | 3:1 (1:0) | ||
| 18:00 | Kasımpaşa SK | - | Beşiktaş | 1:0 (1:0) | ||
| 05.04.2021 | 18:00 | Fenerbahçe | - | Denizlispor | 1:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Beşiktaş | 30 | 20 | 4 | 6 | 63:31 | 32 | 64 |
| 2 |
|
Fenerbahçe | 31 | 19 | 5 | 7 | 55:31 | 24 | 62 |
| 3 |
|
Galatasaray | 31 | 19 | 4 | 8 | 61:30 | 31 | 61 |
| 4 |
|
Trabzonspor | 31 | 16 | 8 | 7 | 39:30 | 9 | 56 |
| 5 |
|
Alanyaspor | 31 | 14 | 7 | 10 | 49:31 | 18 | 49 |
| 6 |
|
Hatayspor | 30 | 14 | 7 | 9 | 51:36 | 15 | 49 |
| 7 |
|
Gaziantep FK | 30 | 12 | 11 | 7 | 44:34 | 10 | 47 |
| 8 |
|
Fatih Karagümrük SK | 31 | 12 | 9 | 10 | 46:38 | 8 | 45 |
| 9 |
|
Sivasspor | 30 | 9 | 14 | 7 | 37:35 | 2 | 41 |
| 10 |
|
Göztepe | 31 | 10 | 10 | 11 | 44:42 | 2 | 40 |
| 11 |
|
Konyaspor | 30 | 10 | 9 | 11 | 37:36 | 1 | 39 |
| 12 |
|
Antalyaspor | 31 | 8 | 15 | 8 | 29:37 | -8 | 39 |
| 13 |
|
Çaykur Rizespor | 30 | 8 | 11 | 11 | 36:47 | -11 | 35 |
| 14 |
|
Kasımpaşa SK | 31 | 9 | 7 | 15 | 34:47 | -13 | 34 |
| 15 |
|
İstanbul Başakşehir | 31 | 8 | 9 | 14 | 35:49 | -14 | 33 |
| 16 |
|
Yeni Malatyaspor | 30 | 7 | 11 | 12 | 38:44 | -6 | 32 |
| 17 |
|
MKE Ankaragücü | 30 | 9 | 5 | 16 | 36:49 | -13 | 32 |
| 18 |
|
Kayserispor | 30 | 8 | 8 | 14 | 23:39 | -16 | 32 |
| 19 |
|
Gençlerbirliği | 30 | 8 | 6 | 16 | 28:52 | -24 | 30 |
| 20 |
|
BB Erzurumspor | 31 | 6 | 9 | 16 | 29:51 | -22 | 27 |
| 21 |
|
Denizlispor | 30 | 6 | 7 | 17 | 26:51 | -25 | 25 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
