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| 13.02.2021 | 13:00 | FC Mynai | - | FK Lviv | 1:2 (0:2) | |
| 13:00 | Zorya Lugansk | - | Desna Chernigov | 2:1 (1:1) | ||
| 16:00 | Dinamo Kiev | - | Olimpik Donetsk | 3:1 (1:1) | ||
| 14.02.2021 | 13:00 | FK Mariupol | - | FK Oleksandriya | 0:1 (0:1) | |
| 13:00 | Kolos Kovalivka | - | Shakhtar Donetsk | 0:0 (0:0) | ||
| 16:00 | Rukh Lviv | - | Vorskla Poltava | 1:1 (1:0) | ||
| 16:00 | SK Dnipro-1 | - | Inhulets Petrove | 2:0 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Dinamo Kiev | 14 | 10 | 3 | 1 | 28:11 | 17 | 33 |
| 2 |
|
Shakhtar Donetsk | 14 | 8 | 6 | 0 | 33:11 | 22 | 30 |
| 3 |
|
Zorya Lugansk | 14 | 6 | 5 | 3 | 26:13 | 13 | 23 |
| 4 |
|
Desna Chernigov | 14 | 6 | 5 | 3 | 19:13 | 6 | 23 |
| 5 |
|
Vorskla Poltava | 14 | 5 | 6 | 3 | 18:11 | 7 | 21 |
| 6 |
|
Olimpik Donetsk | 14 | 6 | 2 | 6 | 23:24 | -1 | 20 |
| 7 |
|
Kolos Kovalivka | 14 | 4 | 7 | 3 | 18:16 | 2 | 19 |
| 8 |
|
FK Oleksandriya | 14 | 5 | 4 | 5 | 20:18 | 2 | 19 |
| 9 |
|
FK Mariupol | 14 | 4 | 4 | 6 | 14:20 | -6 | 16 |
| 10 |
|
FK Lviv | 14 | 4 | 3 | 7 | 11:27 | -16 | 15 |
| 11 |
|
Inhulets Petrove | 14 | 1 | 8 | 5 | 13:22 | -9 | 11 |
| 12 |
|
SK Dnipro-1 | 14 | 3 | 2 | 9 | 18:28 | -10 | 11 |
| 13 |
|
Rukh Lviv | 14 | 1 | 7 | 6 | 13:24 | -11 | 10 |
| 14 |
|
FC Mynai | 14 | 2 | 4 | 8 | 10:26 | -16 | 10 |
| Champions League | |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
