| Kader | Einsätze | ||
| Sortierung |
| Name |  |
 |
 |
 |
 |
 |
 |
 |
 |
| Nemanja Vidić | 2982' | 34 | 33 | 1 | - | 4 | 4 | 1 | 1 |
| Cristiano Ronaldo | 2748' | 33 | 31 | 2 | 5 | 18 | 5 | 1 | - |
| Edwin van der Sar | 2912' | 33 | 33 | - | 1 | - | 1 | - | - |
| Dimitar Berbatov | 2543' | 31 | 29 | 2 | 7 | 9 | 2 | - | - |
| John O'Shea | 1986' | 30 | 20 | 10 | 4 | - | 1 | - | - |
| Wayne Rooney | 2266' | 30 | 25 | 5 | 5 | 12 | 7 | 1 | - |
| Carlos Tévez | 1857' | 29 | 18 | 11 | 8 | 5 | 3 | - | - |
| Michael Carrick | 2041' | 28 | 24 | 4 | 5 | 4 | 3 | - | - |
| Patrice Evra | 2411' | 28 | 28 | - | 4 | - | 6 | - | - |
| Ryan Giggs | 1500' | 28 | 15 | 13 | 3 | 2 | - | - | - |
| Darren Fletcher | 2059' | 26 | 25 | 1 | 9 | 3 | 4 | - | - |
| Ji-Sung Park | 1727' | 25 | 21 | 4 | 10 | 2 | 4 | - | - |
| Rio Ferdinand | 2140' | 24 | 24 | - | 1 | - | 2 | - | - |
| Paul Scholes | 1265' | 21 | 14 | 7 | 6 | 2 | 3 | - | 1 |
| Anderson | 934' | 17 | 11 | 6 | 9 | - | - | - | - |
| Jonny Evans | 1423' | 17 | 16 | 1 | 2 | - | 2 | - | - |
| Gary Neville | 1075' | 16 | 13 | 3 | 4 | - | 3 | - | - |
| Rafael | 1054' | 16 | 12 | 4 | 5 | 1 | 2 | - | - |
| Nani | 549' | 13 | 7 | 6 | 6 | 1 | 1 | - | - |
| Wes Brown | 594' | 8 | 6 | 2 | - | 1 | 3 | - | - |
| Tomasz Kuszczak | 328' | 4 | 3 | 1 | - | - | - | - | - |
| Federico Macheda | 189' | 4 | 2 | 2 | 1 | 2 | 2 | - | - |
| Darron Gibson | 138' | 3 | 1 | 2 | - | 1 | 1 | - | - |
| Rodrigo Possebon | 52' | 3 | - | 3 | - | - | - | - | - |
| Danny Welbeck | 116' | 3 | 1 | 2 | 1 | 1 | - | - | - |
| Richard Eckersley | 49' | 2 | - | 2 | - | - | - | - | - |
| Ben Foster | 180' | 2 | 2 | - | - | - | - | - | - |
| Owen Hargreaves | 114' | 2 | 1 | 1 | - | - | - | - | - |
| Zoran Tošić | 16' | 2 | - | 2 | - | - | - | - | - |
| Fraizer Campbell | 80' | 1 | 1 | - | 1 | - | 1 | - | - |
| Ritchie De Laet | 79' | 1 | 1 | - | 1 | - | - | - | - |
| Manucho | 16' | 1 | - | 1 | - | - | - | - | - |
| Lee Martin | 90' | 1 | 1 | - | - | - | - | - | - |
| Ben Amos | - | - | - | - | - | - | - | - | - |
| James Chester | - | - | - | - | - | - | - | - | - |
| Fábio | - | - | - | - | - | - | - | - | - |
| Ron-Robert Zieler | - | - | - | - | - | - | - | - | - |
England