| Premier League | Sp. | S | U | N | Tore | |||
| Zu Hause | 11 | 6 | 3 | 2 | 28 | : | 19 | |
| Auswärts | 11 | 3 | 1 | 7 | 11 | : | 22 | |
| ∑ | 22 | 9 | 4 | 9 | 39 | : | 41 | |
| Championship | Sp. | S | U | N | Tore | |||
| Zu Hause | 15 | 6 | 4 | 5 | 22 | : | 18 | |
| Auswärts | 15 | 3 | 4 | 8 | 18 | : | 37 | |
| ∑ | 30 | 9 | 8 | 13 | 40 | : | 55 | |
| FA Cup | Sp. | S | U | N | Tore | |||
| Zu Hause | 2 | 2 | 0 | 0 | 2 | : | 0 | |
| Auswärts | 1 | 0 | 0 | 1 | 0 | : | 2 | |
| Neutraler Ort | 2 | 0 | 1 | 1 | 2 | : | 3 | |
| ∑ | 5 | 2 | 1 | 2 | 4 | : | 5 | |
| League Cup | Sp. | S | U | N | Tore | |||
| Auswärts | 2 | 0 | 0 | 1 | 0 | : | 1 | |
| ∑ | 2 | 0 | 0 | 1 | 0 | : | 1 | |
| GESAMT | Sp. | S | U | N | Tore | |||
| Zu Hause | 28 | 14 | 7 | 7 | 52 | : | 37 | |
| Auswärts | 29 | 6 | 5 | 17 | 29 | : | 62 | |
| Neutraler Ort | 2 | 0 | 1 | 1 | 2 | : | 3 | |
| ∑ | 59 | 20 | 13 | 25 | 83 | : | 102 | |
| League Cup | |||||
| 2021/2022 | 3. Runde | Sheffield United | - | Southampton FC | 2:4 (1:1, 2:2) i.E. |
| 2014/2015 | Viertelfinale | Sheffield United | - | Southampton FC | 1:0 (0:0) |
|
Für Spiele, die im Elfmeterschießen entschieden wurden, geht der Spielstand nach 120 Minuten in diese Wertung ein. |
England 
![Southampton FC Women [Frauen]](https://s.hs-data.com/bilder/wappen/mini/33520.gif?fallback=png "Southampton FC Women [Frauen]"){kind=small}
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