Zugänge
| ab | Name | Pos | Mannschaft | Team | ||
|---|---|---|---|---|---|---|
| 08/2021 |  | Roberto Avila | ST |  | FC Edmonton | FC Edmonton |
Abgänge
| ab | Name | Pos | Mannschaft | Team | ||
|---|---|---|---|---|---|---|
| 02/2022 |  | Fabien Garcia | AB |  | San Antonio FC | San Antonio FC |
| 01/2022 |  | Ates Diouf | MF | | San Antonio FC | San Antonio FC |
| 01/2022 |  | Stéfano Pinho | ST |  | Amazonas FC - AM | Amazonas |
| 01/2022 | | Gustavo Rissi | AB |  | Cruzeiro | Cruzeiro |
| 01/2022 | | Gilbert Fuentes | MF |  | San Jose Earthquakes | Earthquakes |
| 01/2022 | | Roberto Avila | ST |  | Houston Dynamo | H. Dynamo |
| 12/2021 | | Elliot Panicco | TW |  | Nashville SC | Nashville SC |
| 12/2021 | | Nick Hinds | AB | | Nashville SC | Nashville SC |
| 12/2021 | | Casey Walls | AB | | San Jose Earthquakes | Earthquakes |
| 12/2021 | | Juan Torres | MF |  | New York City FC | NY City FC |
| 08/2021 | | Sean Okoli | ST |  | Orange County SC | Orange County |
| 08/2021 |  | Jason Johnson | ST |  | FC Tulsa | FC Tulsa |