| 1. Runde | 15.09.2005 | AS Roma | - | Aris Saloniki | 5:1 | ||||
| Gruppe E | 20.10.2005 | Tromsø IL | - | AS Roma | 1:2 |  |
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| Gruppe E | 01.12.2005 | Crvena Zvezda | - | AS Roma | 3:1 | ||||
| 3. Runde | 15.02.2006 | Club Brugge KV | - | AS Roma | 1:2 | ||||
| 3. Runde | 23.02.2006 | AS Roma | - | Club Brugge KV | 2:1 | ||||
| Achtelfinale | 09.03.2006 | Middlesbrough FC | - | AS Roma | 1:0 | ||||
| Achtelfinale | 15.03.2006 | AS Roma | - | Middlesbrough FC | 2:1 |
Ghana