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| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSC Bari | 11 | 6 | 3 | 2 | 14:8 | 6 | 21 |
| 2 |
|
US Avellino | 12 | 5 | 5 | 2 | 13:8 | 5 | 20 |
| 3 |
|
FC Turris | 11 | 5 | 3 | 3 | 16:11 | 5 | 18 |
| 4 |
|
Campobasso | 12 | 5 | 3 | 4 | 14:18 | -4 | 18 |
| 5 |
|
US Catanzaro | 11 | 3 | 5 | 3 | 9:7 | 2 | 14 |
| 6 |
|
Virtus Francavilla | 12 | 4 | 2 | 6 | 9:12 | -3 | 14 |
| 7 |
|
AZ Picerno | 13 | 3 | 4 | 6 | 10:19 | -9 | 13 |
| 8 |
|
Fidelis Andria | 12 | 3 | 3 | 6 | 11:15 | -4 | 12 |
| 9 |
|
SS Monopoli 1966 | 12 | 3 | 3 | 6 | 12:18 | -6 | 12 |
| 10 |
|
Monterosi FC | 13 | 2 | 6 | 5 | 11:19 | -8 | 12 |
| 11 |
|
Palermo FC | 11 | 2 | 5 | 4 | 10:13 | -3 | 11 |
| 12 |
|
SS Juve Stabia | 11 | 2 | 4 | 5 | 10:16 | -6 | 10 |
| 13 |
|
Foggia Calcio | 12 | 1 | 6 | 5 | 12:19 | -7 | 9 |
| 14 |
|
Taranto FC | 13 | 2 | 3 | 8 | 12:24 | -12 | 9 |
| 15 |
|
ACR Messina | 13 | 2 | 3 | 8 | 15:30 | -15 | 9 |
| 16 |
|
Latina Calcio | 12 | 2 | 2 | 8 | 10:20 | -10 | 8 |
| 17 |
|
Vibonese Calcio | 11 | 0 | 4 | 7 | 5:17 | -12 | 4 |
| 18 |
|
Paganese Calcio | 12 | 0 | 3 | 9 | 6:24 | -18 | 3 |
| 19 |
|
Potenza | 11 | 0 | 2 | 9 | 6:25 | -19 | 2 |
| 20 |
|
Calcio Catania | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
|
# Calcio Catania ging im Frühjahr 2022 bankrott und wurde vom professionellen Fußball ausgeschlossen. Alle Saisonspiele des Vereins wurden annulliert. |
