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| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSC Bari | 14 | 7 | 5 | 2 | 17:10 | 7 | 26 |
| 2 |
|
Campobasso | 14 | 6 | 3 | 5 | 18:22 | -4 | 21 |
| 3 |
|
US Avellino | 13 | 5 | 5 | 3 | 13:9 | 4 | 20 |
| 4 |
|
US Catanzaro | 13 | 5 | 5 | 3 | 11:7 | 4 | 20 |
| 5 |
|
FC Turris | 14 | 5 | 4 | 5 | 20:22 | -2 | 19 |
| 6 |
|
Virtus Francavilla | 13 | 4 | 3 | 6 | 9:12 | -3 | 15 |
| 7 |
|
SS Monopoli 1966 | 14 | 4 | 3 | 7 | 13:19 | -6 | 15 |
| 8 |
|
Monterosi FC | 15 | 3 | 6 | 6 | 14:21 | -7 | 15 |
| 9 |
|
AZ Picerno | 14 | 3 | 5 | 6 | 11:20 | -9 | 14 |
| 10 |
|
Foggia Calcio | 14 | 2 | 7 | 5 | 14:20 | -6 | 13 |
| 11 |
|
Fidelis Andria | 13 | 3 | 3 | 7 | 11:17 | -6 | 12 |
| 12 |
|
ACR Messina | 15 | 3 | 3 | 9 | 19:34 | -15 | 12 |
| 13 |
|
Palermo FC | 13 | 2 | 5 | 6 | 12:19 | -7 | 11 |
| 14 |
|
Latina Calcio | 14 | 3 | 2 | 9 | 13:23 | -10 | 11 |
| 15 |
|
SS Juve Stabia | 13 | 2 | 4 | 7 | 11:20 | -9 | 10 |
| 16 |
|
Taranto FC | 15 | 2 | 3 | 10 | 12:28 | -16 | 9 |
| 17 |
|
Vibonese Calcio | 13 | 0 | 4 | 9 | 9:24 | -15 | 4 |
| 18 |
|
Paganese Calcio | 14 | 0 | 4 | 10 | 7:26 | -19 | 4 |
| 19 |
|
Potenza | 13 | 0 | 3 | 10 | 7:28 | -21 | 3 |
| 20 |
|
Calcio Catania | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
|
# Calcio Catania ging im Frühjahr 2022 bankrott und wurde vom professionellen Fußball ausgeschlossen. Alle Saisonspiele des Vereins wurden annulliert. |
