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| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SSC Bari | 16 | 9 | 5 | 2 | 20:11 | 9 | 32 |
| 2 |
|
US Avellino | 16 | 8 | 5 | 3 | 17:9 | 8 | 29 |
| 3 |
|
US Catanzaro | 16 | 6 | 6 | 4 | 16:12 | 4 | 24 |
| 4 |
|
Campobasso | 16 | 6 | 3 | 7 | 22:30 | -8 | 21 |
| 5 |
|
FC Turris | 16 | 5 | 4 | 7 | 20:27 | -7 | 19 |
| 6 |
|
Monterosi FC | 16 | 4 | 6 | 6 | 16:21 | -5 | 18 |
| 7 |
|
SS Monopoli 1966 | 16 | 5 | 3 | 8 | 14:21 | -7 | 18 |
| 8 |
|
Foggia Calcio | 16 | 3 | 8 | 5 | 19:22 | -3 | 17 |
| 9 |
|
AZ Picerno | 16 | 4 | 5 | 7 | 14:23 | -9 | 17 |
| 10 |
|
Virtus Francavilla | 16 | 4 | 4 | 8 | 10:15 | -5 | 16 |
| 11 |
|
Palermo FC | 16 | 3 | 7 | 6 | 18:24 | -6 | 16 |
| 12 |
|
Fidelis Andria | 16 | 3 | 5 | 8 | 12:19 | -7 | 14 |
| 13 |
|
SS Juve Stabia | 16 | 3 | 4 | 9 | 12:24 | -12 | 13 |
| 14 |
|
ACR Messina | 17 | 3 | 4 | 10 | 20:37 | -17 | 13 |
| 15 |
|
Latina Calcio | 17 | 3 | 3 | 11 | 14:27 | -13 | 12 |
| 16 |
|
Taranto FC | 16 | 2 | 4 | 10 | 13:29 | -16 | 10 |
| 17 |
|
Potenza | 16 | 2 | 3 | 11 | 12:31 | -19 | 9 |
| 18 |
|
Paganese Calcio | 16 | 0 | 5 | 11 | 10:30 | -20 | 5 |
| 19 |
|
Vibonese Calcio | 16 | 0 | 5 | 11 | 9:30 | -21 | 5 |
| 20 |
|
Calcio Catania | 0 | 0 | 0 | 0 | 0:0 | 0 | 0 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
|
# Calcio Catania ging im Frühjahr 2022 bankrott und wurde vom professionellen Fußball ausgeschlossen. Alle Saisonspiele des Vereins wurden annulliert. |
